Synthesis and antimicrobial activity of some novel heterocycles containing thiazole, oxazole, thiazine, oxazine and triazole moiety

Indandione 1 was brominated to yield 2-bromoIndandione 2 which on further reacted with substituted thiocarbamides, carbamides, 2-aminothiophenols, 2-aminophenol and triazoles to furnished 3-substituted aniline-2-thia-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 3, 3-substituted aniline-2-oxa-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 4, 2-Thia-5-aza-9-oxo-3,4-(3’-substituted) benzo-7,8-benzo-bicyclo [4.3.0]-1(6) nonene 5, 2-oxa-5-aza-9-oxo-(3, 4)-(7, 8)-dibenzo-bicyclo [4.3.0]-1(6) nonene 6, 3-substituted-(1,2,4) triazolo [4,5-b] [indeno (2,3-e)]-1,3,4-thiadiazine 7 respectively.