Yeast hexokinase is a homodimer consisting of two identical subunits. Yeast hexokinase was inactivated by 2-aminothiophenol at 25 degrees C (pH 9.1). The reaction followed pseudo-first-order kinetics until about 70% of the phosphotransferase activity was lost. About 0.65 mol of 2-aminothiophenol/mol of hexokinase was found to be bound after the 70% loss of the enzyme activity. Completely inacti...

2-(Bromomethyl)-1-sulfonylaziridines were converted into novel 3-sulfonamido-2,3,4,5-tetrahydro-1,5-benzothiazepines upon treatment with 2-aminothiophenol in THF in the presence of K2CO3. Starting from 3-substituted 2-(sulfonyloxymethyl)aziridines, a regio- and stereocontrolled synthesis of trans-2-phenyl- and trans-4-(phenyl or propyl)-3-sulfonamido-2,3,4,5-tetrahydro-1,5-benzothiazepines was ...

The 2-aminothiophenol-based fluorometric assay of Nakano et al. (1973, J. Pharm. Soc. Jpn. 93, 350-353) for monosaccharides has been modified to improve the speed, applicability, and sensitivity of the method. The improved assay is applicable to complex carbohydrates as well as to monosaccharides. Less than 50 ng of carbohydrate in a final volume of 2 ml can be quantitatively measured within 30...

A simple and novel method for the colorimetric detection of Co(2+) was developed based on controlling the oxidation level of methylene blue (MB). After a complex was formed between MB, 2-aminothiophenol (ATP) and copper nitrate (MB-ATP-Cu(2+)), the sensing of Co(2+) showed high selectivity. The mechanism of sensing has also been discussed.

Synthesis, physical and analytical properties of 1-(2H-benzo [b] [1, 4] thiazin-3(4H)-ylidene) hydrazine1, 1-dioxide derivatives are described. These new compounds were synthesized through a sequence of almost quantitative reactions. The commercial starting material 2-aminothiophenol was condensed with β-haloesters, reacted with hydrazine derivatives and oxidized at sulfur atom to obtained sulf...

The synthesis of 2-substituted benzothiazoles has been described using ZnO-nanoparticles as a catalyst. condensation 2-aminothiophenol and aryl/alkyl nitriles resulted in the formation va...

Reaction of 1,2-naphthoquinone with primary amines gives a 2-amino-1,4-naphthoquinone derivative which is equivalent to 1,2 to 1,4 carbonyl transposition. For example the reaction of 1,2-naphthoquinone with 4-methoxyaniline gives 2-(4-methoxyanilino)-naphthoquinone-1,4-(4-methoxyanil) (1) and with n-butylamine gives 2-(butylamino)-naphthoquinone-1,4-butylimine (2) respectively. The compounds 1 ...

A series of heterocyclic acene diimides were synthesized effectively based on the condensation of o-phenylenediamine, 1,2-benzenedithiol, and 2-aminothiophenol with 2,3,6,7-tetrabromo-1,4,5,8-naphthalene tetracarboxylic diimide. The diimides exhibit interesting optical and electrical properties with one of them showing a hole mobility up to 0.02 cm(2) V(-1) s(-1).

A one-pot synthesis of 2-arylbenzothiazoles from the reaction of 2-aminothiophenol and aromatic aldehydes catalysed by cerium (IV) ammonium nitrate (CAN) is reported.

A new Schiff base 2-aminothiophenol furfural self assembled monolayer (SAM) has been fabricated on a bare gold electrode as a novel sensor for determination of dopamine. Electrochemical impedance spectroscopywas utilized to investigate the properties of the Au 2-aminothiophenol furfural self assembled monolayermodified electrode (Au ATF SAM-ME) using the [Fe(CN)6]3-/4- redox couple. The electro...