Maternal and Neonatal Zinc and Copper Levels and Birth Weight

Authors

  • Abbas Heshmati Cardiovascular Research Center, Avicenna (Bu-Ali) Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran
  • Gholamali Maamouri Neonatal Research Center, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
  • Hassan Boskabadi Neonatal Research Center, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
  • Hosein Ayatollahi Neonatal Research Center, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
  • Hosein Mohsenzade Resident of pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran
  • Majid Ghayour-Mobarhan Department of nutrition and biochemistry, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mehran Noria Neonatal Research Center, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
  • Zohre Samirad Head of Educational and Student Services
Abstract:

Introduction Minerals and trace elements such as zinc and copper have significant influence on development and growth of the fetus and newborn. The purpose of this study was to determine the relationship between low birth weight and maternal and neonatal zinc, copper levels. Materials and Methods This case – control study   was done from September 2006 to Sep 2007 consisted of 65 infants with birth weight < 2500 g and 65 infants weighing ≥ 2500g.  Cord and maternal blood samples collected at delivery were analyzed by atomic absorption spectrophotometry for zinc and copper levels.  Results Mean serum zinc levels in maternal (P=0.001) and the cord blood (P=0.49) were 6.35 ± 2.09 µmol/l, 12.77±3.83 mol/l and 7.57±1.75 µmol/l , 13.18±2.69 µmol/l of cases  and control groups ,respectively.The mean copper levels in maternal (P=0.62) and cord blood (P=0.005) were 21.82±4.45 µmol/l, 5.12±1.54 µmol/l and  21.19 ± 5.34 µmol/l and  3.65±2.04 µmol /l of control and case group, respectively. Conclusion This study indicated that there is a relationship between birth weight less than 2500 gr and maternal zinc levels (P

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Journal title

volume 2  issue 1

pages  26- 31

publication date 2011-10-01

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