a study of serum ?2-microglobulin (s?2m) in hemodialysis patients with cellulosis membrane1
نویسندگان
چکیده
?2 microglobulin (?2m) fibril has been recognized as the major factor of dialysis-related amyloidosis. elevated serum levels are thought to be the basis for tissue deposition. in order to evaluate the effect of cellulosis membrane (fb 110) and treatment duration on s?2m levels, we determined serum levels in 23 hemodialyzed patients with end-stage renal failure. s?2m levels were markedly elevated in all patients with a mean of 74.71 (sd=21.2 mg/l, range: 46 mg/l after 2 years hemodialysis-123.8 mg/l after 10 years treatment) that statistically is higher than healthy subjects (p<0.0001). serum ?2m in 19 healthy subjects was 2.36 (sd=0.4 mg/l, rang: 1.58-3.3 mg/l). although in hemodialysis group, no significant correlation was found between s?2m and age or sex but increased serum levels of ?2m had significant correlation with duration of hemodialysis treatment (r=0.53, p<0.01). since the dialysis membrane has a very effective role in clearance of s?2m, we suggest that the particular effort should be made towards improvement of dialysis membranes.
منابع مشابه
Association between serum 2-microglobulin level and infectious mortality in hemodialysis patients.
BACKGROUND AND OBJECTIVES Secondary analysis of the Hemodialysis Study showed that serum beta(2)-microglobulin levels predicted all-cause mortality and that high-flux dialysis was associated with decreased cardiac deaths in hemodialysis patients. This study examined the association of serum beta(2)-microglobulin levels and dialyzer beta(2)-microglobulin kinetics with the two most common causes ...
متن کاملAn Investigation of the Relationship between Beta-2 Microglobulin (β2M) and Inflammatory Factors (Serum Levels of CRP and Albumin) and High Density Lipoproteins (HDL) in Hemodialysis Patients
Background and Objective: Beta-2 Microglobulin (β2M) is a middle molecular weight uremic toxin. Lack of β2M removal leads to β2M accumulation and amyloidosis in hemodialysis patients. The present research aims to determine the relationship between β2M and inflammatory factors, such as C-reactive protein (CRP), albumin, and high-density lipoprotein (HDL) in hemodialysis patie...
متن کاملa study of baudrillards ideas in brian moores fiction
پیدایش مرحله ی جدیدی از نظام سرمایه داری بعد از جنگ جهانی دوم همزمان است با ظهور عصر اطلاعات و رسانه جمعی. در چنین جامعه ای سیر آزادانه ی نشانه ها در فضای بی اساس مجازی بر سرعت فرسایش واقعیت می افزاید. به اعتقاد بودریار، فقدان واقعیت به واسطه ی شبیه سازی آن و تولید حاد واقعیت (hyperreality) پنهان خواهد ماند. این پژوهش بر آن است که جامعه فرانوین توصیف شده در سه رمان بریان مور را با توجه به نظر...
15 صفحه اولمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهرانجلد ۵۸، شماره ۲، صفحات ۶۶-۷۰
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023