Introduction: β2-microglobulin and prolactin are medium-molecular-weight toxins. We believe that the rate of removal these molecules, using filters with two different surfaces, in post- pre-dilution haemodiafiltration, will be interest to literature. Methods: studied, 12 haemodialyzed patients, those, filter surface 2.5 m2 (Group A) or 2.1 B) post-dilution a C). Results: Satisfactory (best post...

welding is a process in which two or more metals are attached by the use of heat and, in some cases, pressure. direct exposure and inhalation of welding fumes causes acute and chronic side effects in humans. kidney damage is one of these important side effects. β2 microglobulin is an 11.8 kilodalton protein and levels increase in the case of some inflammatory and viral diseases, or kidney malfu...

to find if some indices have predictive value for renal complications. we conducted a cross sectional and included 80 patients with the age ranged 5-17 years, all with the proven diagnosis of β-thalassemia major. a urine and 5 ml of blood sample were obtained from all of the cases. biochemical indices such as serum levels of creatinine, na, mg, hb, and ferritin and also urine levels of na, mg, ...

measurement of serum creatinine (cr) and blood urea nitrogen (bun) are used as indicators of glomerular filtration rate. the increased levels of these biomarkers are usually detectable at advanced stages of kidney complications. the aim of this study was to find the interrelationship of beta-2 microglobulin (β2m), bun and cr in streptozotocin (stz)-induced diabetes mellitus in rabbits. diabetes...

Objective. After filtration through glomeruli, β2-microglobulin is reabsorbed in proximal tubules. Increased urinary β2-microglobulin indicates proximal tubule injury and measurement of β2-microglobulin in urine is useful to determine the source of renal injury. Kidney injury molecule-1 (KIM-1) has been characterized as a selective proximal tubule injury marker. This study was designed to evalu...

a1-Microglobulin is a 26-kd protein, widespread in plasma and tissues and wellconserved among vertebrates. a1-Microglobulin belongs to the lipocalins, a protein superfamily with highly conserved 3-dimensional structures, forming an internal ligand binding pocket. The protein, isolated from urine, has a heterogeneous yellow-brown chromophore bound covalently to amino acid side groups around the ...

Beta2-microglobulin was investigated in atypical haemochromatosis patients not homozygous for the C282Y mutation of HFE (OMIM *235200), because the HFE protein binds beta2-microglobulin, and in mice beta2-microglobulin gene knockout causes hepatic iron overload. Six unrelated patients with atypical haemochromatosis were studied. Five patients had normal HFE coding sequence and the sixth was het...