background: zinc has significant effects on structural and functional activities of many proteins and enzymes involved in biological activities, especially the regulation of immune-system. symptoms of zinc toxicity include nausea/vomiting, fever, cough, diarrhea, fatigue, neuropathy, and dehydration. further signs include growth retardation, altered iron function, anemia, copper deficiency, dec...

cadmium (cd) is among the most widespread and toxic heavy metal in several part of the world. its toxicity in soil is becoming a severe threat to living organism worldwide. it is one of the main pollutants in paddy fields near industrial areas and highly toxic to plant growth and development of the plants. cd can be easily taken up by plants and enter the food chain. therefore, precautionary me...

cotton (gossypium hirsutum l. cv. varamin ) an important industrial crop of iran, is grown in 300,000 ha, with an average seed -cotton yield of 1750 kg.ha-1. the main obstacle in the way of increasing average cotton yield is imbalanced fertilizer use. along with urea and triple super phosphate, cotton growers also need k, mg, zn, fe, mn, cu, and b, so these elements’ critical levels should ...

......................................................................................................................................................839 Introduction.................................................................................................................................................839 Purpose and Scope ...................................................................

The Biotic Ligand Model has been previously developed to explain and predict the effects of water chemistry on the toxicity of copper, silver, and cadmium. In this paper, we describe the development and application of a biotic ligand model for zinc (Zn BLM). The data used in the development of the Zn BLM includes acute zinc LC50 data for several aquatic organisms including rainbow trout, fathea...

Introduction: Complications of zinc poisoning are analyzed in several studies. Among these, pulmonary fibrosis are reported. There is some doubts about chronic complications of zinc inhalation. Precise screening programs in zinc mine workers need previous knowledge of relative frequency of chronic complications due to zinc inhalation. So this study is held to recognize the complications and to ...

Tau hyperphosphorylation is thought to underlie tauopathy. Working in a Drosophila tauopathy model expressing a human Tau mutant (hTauR406W, or Tau(∗)), we show that zinc contributes to the development of Tau toxicity through two independent actions: by increasing Tau phosphorylation and, more significantly, by directly binding to Tau. Elimination of zinc binding through amino acid substitution...

Zinc is an essential trace element involved in a wide range of biological processes and human diseases. Zinc excess is deleterious, and animals require mechanisms to protect against zinc toxicity. To identify genes that modulate zinc tolerance, we performed a forward genetic screen for Caenorhabditis elegans mutants that were resistant to zinc toxicity. Here we demonstrate that mutations of the...

Scientists participating in the USGS Abandoned Minelands Initiative have quantified metal concentrations and loadings from mining-related and natural background sources in the upper Animas River of southwestern Colorado, with the goal of guiding remediation decisions by federal landmanagement agencies. We have compared site-specific toxicity thresholds with frequencies of dissolved metal concen...