background: despite the effective pre- and post-exposure treatments, at least 60,000 deaths from rabies occur worldwide every year. post-exposure treatment is considered as one of the most significant measures for preventing human deaths in exposed individuals. the 2-1-1 rabies post-exposure treatment schedule known as zagreb regimen is an abbreviated immunization plan in which a tissue culture...

The Zagreb regimen, an abbreviated intramuscular schedule for rabies vaccination, was developed by I. Vodopija and colleagues of the Zagreb Institute of Public Health in Croatia in the 1980s. It was recommended by WHO as one of the intramuscular (IM) schedules for rabies vaccination in 2010. We reviewed the literature on the immunogenicity, safety, economic burden, and compliance of the Zagreb ...

  Background: Despite the effective pre- and post-exposure treatments, at least 60,000 deaths from rabies occur worldwide every year. Post-exposure treatment is considered as one of the most significant measures for preventing human deaths in exposed individuals. The 2-1-1 rabies post-exposure treatment schedule known as Zagreb regimen is an abbreviated immunization plan in which a tissue cultu...

Introduction: Despite the effective preand post-exposure treatments, at least 60,000 deaths from rabies occur worldwide every year. Post-exposure treatment is considered as one of the most significant measures for preventing human deaths in exposed individuals. The 2-1-1 rabies post-exposure treatment schedule known as Zagreb regimen is an abbreviated immunization plan in which a tissue culture...

The aim of this paper was to assess soft contact lens replacement habits of patients of Contact Lens Clinic, Zagreb University Hospital Department of Ophthalmology, Zagreb, Croatia. During spring of 2010, a survey was conducted in Contact Lens Laboratory, Zagreb University Hospital Department of Ophthalmology, Zagreb, Croatia. 47 completed surveys were collected and analyzed. The results of the...

In this paper, we obtain some upper and lower bounds for the general extended energy of a graph. As an application, we obtain few bounds for the (edge) Zagreb energy of a graph. Also, we deduce a relation between Zagreb energy and edge-Zagreb energy of a graph $G$ with minimum degree $delta ge2$. A lower and upper bound for the spectral radius of the edge-Zagreb matrix is obtained. Finally, we ...

BACKGROUND The aim of this study was to compare the safety and immunogenicity between purified vero cell rabies vaccine (PVRV) and purified chick embryo cell vaccine (PCECV) in patients with WHO category II animal exposure, especially in different age groups. METHODOLOGY/PRINCIPAL FINDINGS In one-year clinical observation after vaccination with PVRV or PCECV under Zagreb (2-1-1) or Essen (1-1...

‎let g=(v,e) be a simple connected graph with vertex set v and edge set e. the first, second and third zagreb indices of g are respectivly defined by: $m_1(g)=sum_{uin v} d(u)^2, hspace {.1 cm} m_2(g)=sum_{uvin e} d(u).d(v)$ and $ m_3(g)=sum_{uvin e}| d(u)-d(v)| $ , where d(u) is the degree of vertex u in g and uv is an edge of g connecting the vertices u and v. recently, the first and second m...

The second Zagreb coindex is a well-known graph invariant defined as the total degree product of all non-adjacent vertex pairs in a graph. The second Zagreb eccentricity coindex is defined analogously to the second Zagreb coindex by replacing the vertex degrees with the vertex eccentricities. In this paper, we present exact expressions or sharp lower bounds for the second Zagreb eccentricity co...