نتایج جستجو برای: wnt inhibitory factor 1

تعداد نتایج: 3433943  

Journal: :iranian journal of blood and cancer 0
ghasemi a ghotaslou a mohammadi m ghaffari k abbasian s

background: in acute myeloblastic leukemia, a large number of tumor suppressor genes are silenced through dna methylation such as cdkn2b & p73. wnt inhibitory factor 1 (wif1) and dickkopf-3 (dkk-1) are negative regulators of wnt signaling pathway. in the present study, we evaluated the methylation status of wif1 and dkk-1 genes in acute myeloblastic leukemia patients. patients and methods: bloo...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2012

Abbasian S, Ghaffari K, Ghasemi A, Ghotaslou A, Mohammadi M,

Background: In acute myeloblastic leukemia, a large number of tumor suppressor genes are silenced through DNA methylation such as CDKN2B & p73. Wnt inhibitory factor 1 (WIF1) and Dickkopf-3 (DKK-1) are negative regulators of Wnt signaling pathway. In the present study, we evaluated the methylation status of WIF1 and DKK-1 genes in acute myeloblastic leukemia patients. Patients and Methods: ...

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