Objective: The aim of this study was to investigate CYP1A interaction of crude extracts (ethanolic, methanolic, hydromethanolic & aqueous) of Withania somnifera and its principal phytoconstituents (withaferin-A and withanolide-A) in rat and human liver microsomes. Methods: In vitro study were carried out in both rat & human liver microsomes while, in vivo CYP1A interaction potential was investi...

Gate the properties of ashwagandha in an attempt to authenticate its use as a.Asgand consists of the roots of Withania somnifera which has various therapeutic actions such as. Withania somnifera Dunal belongs to the family solanaceae.Withania somnifera is a medicinal plant extends over a large area, from the.

In this study the use of plants for medicinal purpose used locally in the treatment of various diseases and we examined for their antioxidant activity. Therefore, the present investigation is part of continuing programme related to the biochemical screening of local plants used in Ancient Indian Medicine, Ayurveda, Siddha and Yunani. An Aqueous root extract of Withania Somnifera (L.) Dunal (Ash...

Infectious Bursal Disease is a severe viral disease of chicken responsible for serious economic losses to poultry farmers. The causative agent, Infectious Bursal Disease virus, is inhibited by nitric oxide. Root extract of the Indian ginseng, Withania somnifera, inhibits Infectious Bursal Disease virus in vitro. Also, Withania somnifera root extract is known to induce nitric oxide production in...

Anti-ulcer activity of methanolic extract of Withania somnifera (Ashwagandha) and its action against stress plus pyloric ligation induced gastric ulcer in rats has been reported. Treatment with Withania somnifera extract (100 mg/Kg/day p.o.) for 15 days significantly reduced ulcer index as compared to control group. Extract also significantly reduced volume of gastric secretion, free acidity an...

Withania somnifera of the family Solanaceae has been considered as an important herb in the traditional Ayurvedic and in the indigenous medical system in Bangladesh for its use in the prevention of different central nervous system (CNS) disorders, especially in the conditions of stress and neurodegenerative diseases. Five different extracts of Withania somnifera root were scrutinized to unfold ...

Withania somnifera Dunal, commonly known as ashwagandha, has been used for centuries in Ayurvedic medicine to increase longevity and vitality. Western research supports its polypharmaceutical use, confirming antioxidant, anti-inflammatory, immune-modulating, and antistress properties in the whole plant extract and several separate constituents. This article reviews the literature pertaining to ...

Plant is oldest existing complete medical significance in the world. Its origins go back nearly 5000 years. In this research article make known on Withania somnifera (Ashwagandha) as Medicinal plants have therapeutic potential due to the presence of natural antioxidants functioning as reducing agents, free radical scavengers and quenchers of singlet oxygen. Majority of different medicinal plant...

background: there are evidences regarding the prevalence of dysfunction in sexual function and behavior in diabetic people. experimental studies revealed a positive effect of withania somnifera on sexual function and behaviors. objective: in this research the effect of withania somnifera on sexual function in diabetic male wistar rats was assessed by measuring the serum levels of testosterone p...

Although some promising results have been achieved by acetylcholinesterase inhibitors, an effective therapeutic intervention in Alzheimer's disease still remains an important goal. Sitoindosides VII-X, and withaferin-A, isolated from aqueous methanol extract from the roots of cultivated varieties of Withania somnifera (known as Indian Ginseng), as well as Shilajit, a pale-brown to blackish brow...