background: palliative whole brain radiotherapy (wbrt) has been the standard treatment for brain metastases. ionizing radiation is known to be one of the most potent cataractogenic agents. we aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (oar) in patients with brain metastasis who undergone wbrt. materials and methods: ten conse...

Abstract AIMS Cerebral metastases from extra-cranial primary cancer carries a poor prognosis. For patients in whom surgical resection or SRS are not suitable, local control rates poor. There is considerable debate surrounding the value of whole brain radiotherapy this patient cohort terms control, survival and functional status. We aimed to measure receiving at Norfolk Norwich University Hospit...

Whole brain radiotherapy (WBRT) is a mainstay of treatment in patients with both identifiable brain metastases and prophylaxis for microscopic disease. The use of WBRT has decreased somewhat in recent years due to both advances in radiation technology, allowing for a more localized delivery of radiation, and growing concerns regarding the late toxicity profile associated with WBRT. This has pro...

Brain metastases are the most common malignant adult intracranial tumors, occurring in approximately 10-30% of cancer patients, and generally lead to a poor prognosis. The incidence has been steadily rising, likely due to longer survival from newer systemic therapies and increased utilization of magnetic resonance imaging. Historically, whole-brain radiotherapy has been a standard of care for t...

BACKGROUND An important issue in palliative radiation oncology is the whether whole-brain radiotherapy should be added to radiosurgery when treating a limited number of brain metastases. To optimize personalized treatment of cancer patients with brain metastases, the value of whole-brain radiotherapy should be described separately for each tumor entity. This study investigated the role of whole...