conclusions the etiology of exchange transfusion was unidentified in most cases; however, abo incompatibility was the most prevalent cause of hyperbilirubinemia. complications were common after exchange transfusion and should be considered carefully. patients and methods a retrospective study was performed on 28 days old infants who received exchange transfusion due to severe hyperbilirubinemia...

background: mostly seen toxicities following vancomycin are ototoxicity and nephrotoxicity. we here report a very low birth weight preterm neonate who developed severe episodes of apnea after accidental iatrogenic vancomycin overdose, responsive to treatment with double volume exchange transfusion. case report: a preterm neonate weighing 1380 grams received two doses of 10-fold of the normal do...

background: bilirubin encephalopathy is a clinical syndrome, associated with bilirubin toxicity in the central nervous system, resulting in chronic and permanent sequelae. it has been estimated that approximately 60% and 80% of term and preterm newborns develop jaundice in the first week of life, respectively. in the present study, we aimed to determine the prevalence, morbidity, and mortality ...

Accidental overdose of chemotherapy drugs including vinblastin (VBL) have been reported in the literature. As VBL overdose is potentially fatal, we decided to introduce a 2-year-old girl affected by langerhans’ cell histiocytosis who was accidentally injected 10-times the prescribed dose of VBL (16 mg), and was saved with whole blood double exchange transfusion at 8 and 20 hrs after the acciden...

Background: The incidence of glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in Iran is estimated at 10-14.9%.  The donor blood in blood banks is not screened routinely for this enzyme deficiency and such blood may be used for neonatal exchange transfusion.Objective: To study the effect of G-6-PD deficient blood in neonatal exchange blood transfusion.Methods: In a prospective study, serum...

accidental overdose of chemotherapy drugs including vinblastin (vbl) have been reported in the literature. as vbl overdose is potentially fatal, we decided to introduce a 2-year-old girl affected by langerhans’ cell histiocytosis who was accidentally injected 10-times the prescribed dose of vbl (16 mg), and was saved with whole blood double exchange transfusion at 8 and 20 hrs after the acciden...

We wish to thank our neurosurgical colleagues Mr. P. Harris, Mr. J. F. Shaw, and Mr. G. N. N. Reddy; and also Professor Sir John Bruce and Dr. A. Brownfie Smith for their help with some general surgical and otorhinolaryigological aspects respectively of Case 5. We are particularly grateful to Dr. A. S. Brown, consultant anaesthetist, and Dr. A. A. Donaldson, consultant radiologist, for their sk...