vox2

A new insight into viral proteins as Immunomodulatory therapeutic agents: KSHV vOX2 a homolog of human CD200 as a potent anti-inflammatory protein

2016

Maryam Mousavinezhad-Moghaddam Abbas Ali Amin Houshang Rafatpanah Seyed Abdol Rahim Rezaee

The physiologic function of the immune system is defense against infectious microbes and internal tumour cells, Therefore, need to have precise modulatory mechanisms to maintain the body homeostasis. The mammalian cellular CD200 (OX2)/CD200R interaction is one of such modulatory mechanisms in which myeloid and lymphoid cells are regulated. CD200 and CD200R molecules are membrane proteins that t...

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A new insight into viral proteins as Immunomodulatory therapeutic agents. KSHV vOX2 a homolog of human CD200 as a potent anti-inflammatory protein

Journal: Iranian Journal of Basic Medical Sciences 2016

Abbas Ali Amin Houshang Rafatpanah, Maryam Mousavinezhad-Moghaddam Seyed Abdol Rahim Rezaee,

The physiologic function of the immune system is defense against infectious microbes and internal tumour cells, Therefore, need to have precise modulatory mechanisms to maintain the body homeostasis. The mammalian cellular CD200 (OX2)/CD200R interaction is one of such modulatory mechanisms in which myeloid and lymphoid cells are regulated. CD200 and CD200R molecules are membrane proteins that t...

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a new insight into viral proteins as immunomodulatory therapeutic agents. kshv vox2 a homolog of human cd200 as a potent anti-inflammatory protein

Journal: :iranian journal of basic medical sciences 0

maryam mousavinezhad-moghaddam department of physiology, biology division, faculty of sciences, ferdowsi university of mashhad, mashhad, iran abbas ali amin department of immunology, faculty of medicine, kurdistan university of medical sciences, sanandaj, iran houshang rafatpanah immunology research centre, bu-ali research institute, mashhad university of medical sciences, mashhad, iran seyed abdol rahim rezaee inflammation and inflammatory diseases research center, faculty of medicine, mashhad university of medical sciences, mashhad, iran

the physiologic function of the immune system is defense against infectious microbes and internal tumour cells, therefore, need to have precise modulatory mechanisms to maintain the body homeostasis. the mammalian cellular cd200 (ox2)/cd200r interaction is one of such modulatory mechanisms in which myeloid and lymphoid cells are regulated. cd200 and cd200r molecules are membrane proteins that t...

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Structural properties of a viral orthologue of cellular CD200 protein: KSHV vOX2

Journal: :Virology 2015

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Comparison of the Gene Coding Contents and Other Unusual Features of the GC-Rich and AT-Rich Branch Probosciviruses

2016

Paul D. Ling Simon Y. Long Jian-Chao Zong Sarah Y. Heaggans Xiang Qin Gary S. Hayward

Nearly 100 cases of lethal acute hemorrhagic disease in young Asian elephants have been reported worldwide. All tested cases contained high levels of elephant endotheliotropic herpesvirus (EEHV) DNA in pathological blood or tissue samples. Seven known major types of EEHVs have been partially characterized and shown to all belong to the novel Proboscivirus genus. However, the recently determined...

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Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus.

Journal: :Journal of virology 2002

Chuang-Jiun Chiou Lynn J Poole Peter S Kim Dolores M Ciufo Jennifer S Cannon Colette M ap Rhys Donald J Alcendor Jian-Chao Zong Richard F Ambinder Gary S Hayward

The ORF74 or vGCR gene encoded by Kaposi's sarcoma-associated herpesvirus (KSHV; also called human herpesvirus 8) has properties of a ligand-independent membrane receptor signaling protein with angiogenic properties that is predicted to play a key role in the biology of the virus. We have examined the expression of vGCR mRNA and protein in primary effusion lymphoma (PEL) cell lines, PEL and mul...

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The English strain of rat cytomegalovirus (CMV) contains a novel captured CD200 (vOX2) gene and a spliced CC chemokine upstream from the major immediate-early region: further evidence for a separate evolutionary lineage from that of rat CMV Maastricht

Journal: :Journal of General Virology 2005

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