نتایج جستجو برای: vivo study

تعداد نتایج: 4202132  

2009
Kimi Yamakoshi Akiko Takahashi Fumiko Hirota Rika Nakayama Naozumi Ishimaru Yoshiaki Kubo David J. Mann Masako Ohmura Atsushi Hirao Hideyuki Saya Seiji Arase Yoshio Hayashi Kazuki Nakao Mitsuru Matsumoto Naoko Ohtani Eiji Hara

Expression of the p16(Ink4a) tumor suppressor gene, a sensor of oncogenic stress, is up-regulated by a variety of potentially oncogenic stimuli in cultured primary cells. However, because p16(Ink4a) expression is also induced by tissue culture stress, physiological mechanisms regulating p16(Ink4a) expression remain unclear. To eliminate any potential problems arising from tissue culture-imposed...

Journal: :Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 2011
A Tulga Ulus Nilüfer N Turan Ferda Pınarlı Burak Erdolu Serdar Tuncer Ersin Fadıllıoğlu Tuncay Delibaşı

2015
Xinzhe Yu Yang Di Chao Xie Yunlong Song Hang He Hengchao Li Xinming Pu Weiyue Lu Deliang Fu Chen Jin

BACKGROUND AND OBJECTIVES Gemcitabine (Gem) is far from satisfactory as the first-line regimen for pancreatic cancer, and the emergence of albumin nanoparticles offers new hope for the delivery of Gem. In this study, Gem-loaded human serum albumin nanoparticles (Gem-HSA-NPs) were successfully synthesized, characterized, and tested on a BxPC-3 cell line both in vitro and in vivo. MATERIALS AND...

Journal: :research in pharmaceutical sciences 0

the water content of the epidermis is a main factor in maintaining skin smoothness and elasticity and preventing skin dryness. occlusive products can greatly affect skin hydration by forming a barrier on the skin following the topical administration of oil-based formulations. these products repair the skin barrier by restoring the skin lipids as well. solid lipid nanoparticles (slns) have recen...

Journal: :Development 2013
Y Albert Pan Tom Freundlich Tamily A Weissman David Schoppik X Cindy Wang Steve Zimmerman Brian Ciruna Joshua R Sanes Jeff W Lichtman Alexander F Schier

Advances in imaging and cell-labeling techniques have greatly enhanced our understanding of developmental and neurobiological processes. Among vertebrates, zebrafish is uniquely suited for in vivo imaging owing to its small size and optical translucency. However, distinguishing and following cells over extended time periods remains difficult. Previous studies have demonstrated that Cre recombin...

Journal: :Vision Research 2010
Clive J. Wolsley Kathryn J. Saunders Giuliana Silvestri Roger S. Anderson

The spatial variation in central retinal function determined from mfERG was compared to co-localised measurements of cone density in two normal subjects. Individual cone cells in the parafoveal region of the retina were identified from 1 degrees x1 degrees images of the photoreceptor mosaic using a modified Heidelberg retina tomograph (HRT). The variation in cone density compared well with prev...

Journal: :iranian endodontic journal 0
shahriar shahi associate professor, dental and periodontal disease research center, faculty of dentistry, tabriz university of medical sciences, tabriz, iran. saeed rahimi associate professor, department of endodontics, faculty of dentistry, tabriz university of medical sciences, tabriz, iran. amin salem milani assistant professor, dental and periodontal disease research center, tabriz university of medical sciences, tabriz, iran. researcher, iranian center for endodontic research, shahid beheshti university of medical sciences, tehran, iran. mohammad asghari jafarabadi assistant professor, department of statistics and epidemiology, faculty of health and nutrition, tabriz university of medical sciences, tabriz, iran. gholam reza djoorabbaf naghsh dentist

introduction: determination of the canal working length with radiographs has many drawbacks. electronic apex locators have been developed to overcome some of these problems. recently, a newly designed apex locator called novapex has been introduced. all the studies conducted to determine the accuracy of novapex have been carried out in-vitro on extracted teeth. the aim of this in vivo study was...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه گیلان - دانشکده علوم پایه 1391

از بین بردن سلول های بدخیم با استفاده از تأثیر پرتو های یونساز بر بافت زنده یکی از موثرترین روش ها در درمان تومورهای سرطانی محسوب می شود. مبانی حفاظت پرتوی ایجاب می کند که هر نوع پرتو گیری توجیه پذیر و بهینه باشد. به علاوه برای کسب نتیجه درمانی مطلوب، باید موازنه دقیقی بین دُز رسیده به بافت هدف از یک سو و دُز رسیده به بافت سالم از سوی دیگر برقرار شود. کنترل واقعی درمان و آگاهی از آنچه در عمل رخ م...

Journal: :iranian journal of pharmaceutical research 0
nima naderi department of pharmacology and toxicology, school of pharmacy, shahid beheshti university of medical science, tehran, iran

Journal: :journal of arthropod-borne diseases 0
ersenaydın yağmur alaşehir vocational school, celal bayar university, alaşehir, manisa, turkey. özcan özkan drug and medical device agency of turkey, turkey. kzafer karaer department of entomology and protozoology, faculty of veterinary medicine, ankara university, turkey.

background : in this study, we investigated the lethal potency, electrophoretic protein pattern and in vivo effects of hottentotta saulcyi scorpion venom in mice. methods : scorpions were collected at night, by using a uv lamp from mardin province, turkey. venom was obtained from mature h. saulcyi scorpions by electrical stimulation of the telson. the lethality of the venom was determined by i....

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