Backgrounds. VitB6 deficiency has been associated with a number of adverse health effects. However, the effects of VitB6 in metabolic syndrome are poorly understood. Methods. VitB6 (50 mg/kg/day) was given to Apoe (-/-) mice with hkdigh-fat diet (HFD) for 8 weeks. Endothelial dysfunction, insulin resistance, and hepatic lipid contents were determined. Results. VitB6 administration remarkably in...

abstract [1]   background and objective:nausea and vomiting is the most common complication in the pregnancy but hasn't paid much attention to it. the use of medication especially in-the first weeks of pregnancy may cause stress in pregnant women and their families because of teratogenicity. this is a randomized, double blind clinical trial study. the aim of this study is to investigate th...

OBJECTIVE Ionic magnesium (Mg(2+)) depletion has long been known to cause hyperexcitability with convulsive seizures in rodents, effects that have been reversed by treatment with magnesium (Mg). Metabolic disorders and genetic alterations are suspected in this pathology, in which Mg(2+) transport and intracellular distribution may be reduced without change in serum Mg(2+) concentrations. We eva...

BACKGROUND Difficulty in cervical dilatation is a hard situation during the procedure of diagnostic dilatation and curettage in some cases. This study was performed to evaluate the effect of vaginal misoprostol for cervical priming before diagnostic dilatation and curettage. METHODS In this study 56 women were selected as the candidates for dilatation and curettage. The study was double blind...

  Neurodegenerative disorders are a major public health problem worldwide with huge socioeconomic effect. Recent evidence suggests that neurodegeneration is not only caused by genetic factors but also affected by environmental factors including nutrients. Environmental influences have been shown to cause epigenetic modifications in the brain with long-lasting effects on behavior if they occur i...

The paper presents an application of phosphatidylcholine 45% (PC 45) and polyvinylpyrrolidone (PVP) in formulations of magnesium salts such as Mg(VitB6) and Mg(VitB6Arg) prepared by solid dispersion (SD) techniques. The evaluation of influence of the selected carriers on some physicochemical properties of solid dispersions and on the absorption process of Mg +2 ions in vitro were made. An infra...

background: difficulty in cervical dilatation is a hard situation during the procedure of diagnostic dilatation and curettage in some cases. this study was performed to evaluate the effect of vaginal misoprostol for cervical priming before diagnostic dilatation and curettage. methods: in this study 56 women were selected as the candidates for dilatation and curettage. the study was double blind...