the aim of this retrospective statistical study was to determine the prevalcence and frequency of age and sex distributions of pemphigus disease. pemphigus disease classified as autoimmune bullous dermatoses which is a chronic mucocutaneous disease.this study was performed in razi hospital and department of oral pathology of dental school, tehran university of medical sciences. the most frequen...

Pemphigoid diseases are a group of well defined autoimmune disorders. The most common of these diseases is bullous pemphigoid, which. Abstract Bullous pemphigoid BP is a blistering skin disease. Plex and includes bullous pemphigoid, pemphigoid gestationis, mucous.Bullous pemphigoid BP is an autoimmune subepidermal bullous dermatosis defined. Http:www.orpha.netdatapathoGBukBullousPemphigoid.pdf....

BACKGROUND An association of bullous pemphigoid with neurological disorders has been reported. The objectives of this study were to review the clinical characteristics of patients with bullous pemphigoid and compare the association between bullous pemphigoid and various neurological disorders and comorbidities. METHODS This was a retrospective case-control study involving 43 patients with bul...

Bullous pemphigoid is a subepidermal autoimmune blistering disease associated with autoantibodies to the hemidesmosomal bullous pemphigoid antigens 180 and 230. Most sera from bullous pemphigoid patients recognize epitopes within the N-terminal NC16A portion of the bullous pemphigoid 180 ectodomain. Using cryosections of human skin, patients' sera were shown to generate dermal-epidermal separat...

bullous pemphigoid is an immunobullous disease with high mortality and morbidity. different aspects and characteristics in the patients vary in different areas in the world. our objective was to study clinical and demographic characteristics of bullous pemphigoid in iranian patients. in a retrospective descriptive study, we reviewed 122 patients with bullous pemphigoid within 1987-2007. demogra...

PURPOSE Little is known about the behavior of the endothelial cell (EC) layer following keratoplasty. In vitro experiments suggested that the peripheral endothelium might have a higher regenerative capacity than the central endothelium, and some authors hypothesized that endothelial progenitor cells are present in the limbal area. Thus, we analyzed the corneal endothelial regenerative capacity ...

Bullous mycosis fungoides is a rare entity of cutaneous T-cell lymphomas; however, it can be particularly aggressive with an unfavorable prognosis. Mechanism of formation of bullous lesions in bullous lymphoma remains poorly understood, it can be explained by excessive epidermotropism or tumor infiltration’s toxicity. We report the case of a bullous erythrodermic mycosis fungoides.

OBJECTIVE Sub-epidermal bullous disorders belong to immunobullous diseases which develop as a result of autoantibody action against epidermal basement membrane proteins. Clinically, they are tense bullae and do not rupture easily. They are classified into various forms based on histopathology and direct immunofluorescence patterns. This study was undertaken to assess the incidence of various su...

Bullous pemphigoid is an autoimmune subepidermal blistering dermatosis that is uncommon in childhood. We report a case of a female infant, 3 months old, which presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. The authors used immunohistochemical staining for collagen type IV that allowed the differentiation of bullous pemphigoid from other subepidermal...

pemphigoid gestationis (pg) is a rare autoimmune bullous dermatosis of pregnancy usually presents in the second or third trimester. it is characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae within the lesions. pathogenesis of pg is not fully established, however, most patients develop circulating autoantibodies targeting the bullous pemphigoid (bp) 18...