BACKGROUND The role of sclerotherapy for acute variceal bleeding is challenged by vasoactive drugs and by ligation. AIM A meta-analysis was performed to evaluate whether sclerotherapy remains a gold standard in acute variceal bleeding. METHODS Sclerotherapy was evaluated across four randomized trial groups: (a) combined with vasoconstrictors vs. vasoconstrictors alone (five trials, with 400...

Vasoconstrictors are commonly used with local anesthetics to control pain in dental practice. This is related the role of vasoconstrictors alpha 1 receptor smooth muscle peripheral blood vessels. able constrict vessels area around injection site, so that there a decrease absorption anesthetic drugs tissue. These conditions also contribute prolongation duration action, depth anesthesia and syste...

This article is the first of a series on pharmacological interactions involving medicaments commonly prescribed and/or used in odontology: vasoconstrictors in local anaesthetics and anti-inflammatory and anti-microbial analgesics. The necessity for the odontologist to be aware of adverse reactions as a result of the pharmacological interactions is due to the increase in medicament consumption b...

BACKGROUND Adrenergic vasoconstrictors are commonly used by dentists to enhance the pain-relieving action of local anesthetics and to control local bleeding. Although normally considered safe for these applications, vasoconstrictors can participate in drug interactions that potentially are harmful to patients. METHODS The faculty of a March 1998 symposium entitled "Adverse Drug Interactions i...

Reading group: Jacques Bayssière (dentist, Montpellier, France) Jean-Pierre Bernard (stomatologist, Geneva, Switzerland) Jean-Loup Coudert (dentist, Lyons, France) Damien Duran (dentist, Toulouse, France) Ahmed Feki (dentist, Strasbourg, France) Jean-Christophe Fricain (dentist, Bordeaux, France) Patrick Girard (dentist, Paris, France) Jean-Claude Harnet (dentist, Strasbourg, France) Jacques Je...

BACKGROUND The effect of vasoconstrictors in prolonged cardiopulmonary resuscitation (CPR) has not been fully clarified. OBJECTIVES To evaluate adrenaline and vasopressin pressure effect, and observe the return of spontaneous circulation (ROSC). METHODS A prospective, randomized, blinded, and placebo-controlled study. After seven minutes of untreated ventricular fibrillation, pigs received ...

INTRODUCTION Dynamic obstruction of right ventricle outflow tract (RVOTO) is a rare condition that may acutely cause severe heart failure. It has been reported in some hypertrophic cardiomyopathies, after lung transplantation, and in some cases of hemodynamic instability after cardiopulmonary bypass. PRESENTATION OF CASE We report the case of a 71-year-old man who developed severe hypotension...

A man suffered severe hypotension down to 20~30 mmHg when he received a surgical remove of glioma. This hypotension was hard to treat with many ways due to the blood pressure did not show any response to many vasoconstrictors, such as: adrenaline, norepinephrine, dopamine, and Aramine etc. A rapid injection of lidocaine 200 mg from right femoral vessel showed an efficient effect on promoting bl...