نتایج جستجو برای: vascular endothelial growth factor receptor

تعداد نتایج: 2100290  

Journal: :international journal of reproductive biomedicine 0
pooneh nikuei kianoosh malekzadeh minoo rajaei azim nejatizadeh nasrin ghasemi

preeclampsia is an important pregnancy disorder with serious maternal and fetal complications which its etiology has not been completely understood yet. early diagnosis and management of disease could reduce its potential side effects. the vascular endothelial growth factor (vegf) family including vegf-a is the most potent endothelial growth factor which induces angiogenesis and endothelial cel...

Journal: :iranian journal of pathology 2008
mitra mehrazma khadijeh arjomandi rafsanjani behzad torkamanipoor

background and objective: vascular endothelial growth factor (vegf) and its receptors (vegf-r1 and r2) are major regulators of angiogenesis. this study was designed to assess serum levels of vegf and vegf-r1 and their prognostic significance in newly diagnosed childhood acute leukemia. materials and methods: for this purpose, vegf and vegf-r1 were determined using enzyme linked immuno-sorbant a...

Journal: :iranian journal of allergy, asthma and immunology 0
ebrahim kouchaki department of neurology, kashan university of medical sciences, kashan, iran bentolhoda otroshi shahreza student research committee, kashan university of medical sciences, kashan, iran saiedeh faraji student research committee, kashan university of medical sciences, kashan, iran hassan nikoueinejad nephrology and urology research center, baqiyatallah university of medical sciences, tehran, iran mojtaba sehat department of community medicine, kashan university of medical sciences, kashan, iran

previous studies have demonstrated that vascular endothelial growth factor (vegf) can trigger angiogenesis as well as inflammation through binding to its membranous receptor-1 on endothelial and inflammatory cells. we aimed to correlate the circulatory number of cells expressing such receptor as well as the serum level of vegf and the soluble form of its receptor-1 (svegfr1) to the severity of ...

Journal: :iranian biomedical journal 0
leszek latos-grazynski piotr ziolkowski piotr chmielewski beata j.osiecka symonowicz krzysztof symonowicz1 beata j.osiecka piotr chmielewski piotr ziolkowski leszek latos-grazynski andrzej bronowicz

the role of angiogenic molecules, like vascular endothelial growth factor (vegf) and fibroblast growth factor (fgf) in tumor angiogenesis was well confirmed. photodynamic therapy (pdt) action is, to very high degree, based on tumor vasculature damage. therefore, it seemed to be important to evaluate growth factor receptors after pdt. the extent of receptor expression was studied by immuno-histo...

Journal: :reports of biochemistry and molecular biology 0
mohsen azimi-nezhad

vascular endothelial growth factor (vegf) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. vegf is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kda produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly t ...

Journal: :journal of basic and clinical pathophysiology 2015
fatemeh hajghasemi abbas mirshafiey

background and objective: vascular endothelial growth factor (vegf) is a cytokine which is overexpressed in many malignant cancers including leukemia. vegf plays an important role in tumor invasion and metastasis. determination of the pattern of vegf expression in human leukemic cell lines could be useful not only in screening of new antileukemic agents but also to study the mechanism of their ...

Journal: :iranian red crescent medical journal 0
moslem jafari sani biochemistry department, school of medicine, shahroud university of medical sciences, shahroud, ir iran foad yazdi biotechnology department, faculty of medicine, tehran university of medical sciences, tehran, ir iran masoomeh masoomi karimi immunology department, school of medicine, torbat heydariyeh university of medical sciences, torbat heydariyeh, ir iran javad alizadeh department of molecular medicine, biotechnology research center, pasteur institute of iran, tehran, ir iran majid rahmati biotechnology department, faculty of medicine, tehran university of medical sciences, tehran, ir iran ali zarei mahmudabadi biochemical department, chemical injuries research center, baqiyatallah university of medical sciences, tehran, ir iran; biochemical department, chemical injuries research center, baqiyatallah university of medical sciences, tehran, ir iran. tel: +98-9123277532, fax: +98-2122830262

background angiogenesis is an important biological process involved in the proliferation of endothelial cells, tumor growth and metastasis. vascular endothelial growth factor (vegf) is considered as a prominent regulator of angiogenesis which exerts the aforementioned effect(s) through its respective receptors (vegfr1 and vegfr2). vegf receptors are targeted as a therapeutic candidate for cance...

Dijle Kipmen-Korgun, Emin Korgun, Gizem Korkmaz, Muge Molbay, Murat Ozekinci,

Trophoblast stem cells develop from polar trophoectoderm and give rise to the cells that generate the placenta. Trophoblast cells are responsible for the uterinal invasion and vascular remodeling during the implantation of the embryo. However this knowledge is not yet to be confirmed for trophoblast progenitor cells (TPCs). In this study, we aimed to demonstrate that human TPCs (hTPCs) express ...

Andrzej Bronowicz, Beata J.Osiecka, Krzysztof Symonowicz1, Leszek Latos-Grazynski, Piotr Chmielewski, Piotr Ziolkowski,

The role of angiogenic molecules, like vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF) in tumor angiogenesis was well confirmed. Photodynamic therapy (PDT) action is, to very high degree, based on tumor vasculature damage. Therefore, it seemed to be important to evaluate growth factor receptors after PDT. The extent of receptor expression was studied by immuno-histo...

Journal: :medical journal of islamic republic of iran 0
noushin jalayer naderi department of oral and maxillofacial pathology, faculty of dentistry, shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه شاهد (shahed university) farrokh tirgari pathology department, institute cancer, tehran university of medical sciences, tehran, iran. [email protected] 3. dds, shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) zahra keshavarz shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه شاهد (shahed university)

background: new blood vessels formation is a critical step in tumor progression. vascular density affects the clinical outcome and prognosis of malignant tumors. the aim of this study was to investigate the relation between the vascular endothelial growth factor (vegf) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (oscc).   method...

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