نتایج جستجو برای: variola major

تعداد نتایج: 619747  

2009
Amanda E. Chambers Melissa M. Dixon Steven P. Harvey

Variola major, the causative agent of smallpox, has been eradicated from nature. However, stocks still exist; thus, there is a need for relevant decontamination studies, preferably with nonpathogenic simulants. Previous studies have shown a similarity in response of vaccinia virus and variola major to various decontaminants and thermal inactivation. This study compared vaccinia and fowlpox viru...

Journal: :Emerging Infectious Diseases 2011

ژورنال: :مجله دانشگاه علوم پزشکی مازندران 0
محمدرضا رهنمون mohammad reza rahnemon محمدجواد سبحانی فر mohammad javad sobhanie far محمدرضا حق شناس mohammad reza haghshenas

ریشه کنی موفقیت آمیز آبله در 33 سال گذشته در دنیا به واسطه واکسن موثر بر ضد آن و عدم ایمنی افراد در حال حاضر موجب شد که این ویروس عامل خوبی به عنوان یک سلاح بیولوژیک مورد توجه قرار گیرد. بیماری آبله، بیماری ویروسی حاد با قابلیت سرایت فوق العاده شدید و خطرناکی است که در اثر آلودگی با ویروس واریولای ماژور از خانواده پاکس ویروس ایجاد می شود. عامل بیماری در منبع عفونت می تواند ماه ها باقی بماند و و...

Journal: :Journal of General Virology 1967

2011
J. Michael Lane

After the recent summary of World Health Organization-authorized research on smallpox, several clinical issues remain. This policy review addresses whether early hemorrhagic smallpox is disseminated intravascular coagulation and speculates about the cause of the high mortality rate among pregnant women and whether ocular smallpox is partly the result of trachoma or vitamin A deficiency. The joi...

2017
Petr Pajer Jiri Dresler Hana Kabíckova Libor Písa Pavel Aganov Karel Fucik Daniel Elleder Tomas Hron Vitezslav Kuzelka Petr Velemínsky Jana Klimentova Alena Fucikova Jaroslav Pejchal Rita Hrabakova Vladimir Benes Tobias Rausch Pavel Dundr Alexander Pilin Radomir Cabala Martin Hubalek Jan Stríbrny Markus H. Antwerpen Hermann Meyer

Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free. Therefore, genetic information of these strains can represent only the very last fraction of a long evolutionary process. Based on the genomes of 48 strains, two clades are differentiated: Clade 1 includ...

حق شناس, محمدرضا, رهنمون , محمدرضا, سبحانی فر, محمدجواد,

Smallpox is a serious infectious disease to have ever afflicted mankind. Smallpox is caused by variola virus, which belongs to a family of viruses known as poxviridae. Pox viruses are large DNA viruses which are 200-400 nm. The smallpox prodrome is characterized by the sudden on-set of high fever (38.5°C-40.5°C) and malaise 10 to 14 days after exposure. As populations grew and migrated, the dis...

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