Background: Varicella-zoster infection is a serious and potentially fatal disease, especially among newborns.Several studies have described postnatal varicella zoster exposure among neonates and reported on the efficacy of varicella-zoster immunoglobulins (VZIG) used as post-exposure prophylaxis. Unfortunately, VZIG is not available in Jordan. A limited number of studies have investigated the e...

The objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella and zona history for detecting susceptible subjects. Personnel of Imam Reza hospital (Kermanshah-Iran) and students were recruited and a 5 mL blood sample was obtained from all participants....

case presentation we describe a case of a previously healthy child who presented with sepsis due to varicella gangrenosa. while she initially responded well to a conservative antibiotic and acyclovir treatment, her subsequent rapid deterioration required urgent and repeated debridement. conclusions this report highlights the significance of prompt diagnosis and early surgical intervention for m...

the objective of this study was to assess the seroprevalence of varicella antibodies in healthcare workers and students of healthcare professions and to determine the validity of the self-reported varicella and zona history for detecting susceptible subjects. personnel of imam reza hospital (kermanshah-iran) and students were recruited and a 5 ml blood sample was obtained from all participants....

conclusions in this region, a significant proportion of children are susceptible to vzv, severe varicella and it’s complications at older ages. it is recommended for varicella vaccine to be added to routine childhood vaccination programs and also to be injected to susceptible adolescents. negative history of varicella would be a predictor of varicella antibody status in children and young adult...

background and objectives: varicella–zoster virus (vzv) is a human herpes virus that usually attacks young children and commonly causes chicken pox (varicella). following primary infection, a lifelong latent infection is established. the virus often reactivates during adulthood or senesces to cause shingles (zoster). little is known regarding the genotypes of varicella in kuwait. the aim of thi...

BACKGROUND Varicella vaccine is available in the private sector in China, with a single dose currently recommended for children aged ≥12 months. We investigated a varicella outbreak in a school in Beijing with high varicella vaccination coverage to describe the outbreak, examine risk factors for vaccine failure, and calculate vaccine effectiveness. METHODS A varicella case was defined as an a...

Before availability of varicella vaccine in the United States, an estimated 4 million varicella cases, 11,000-13,500 varicella-related hospitalizations, and 100-150 varicella-related deaths occurred annually. The varicella vaccination program was implemented in the United States in 1996 as a 1-dose routine childhood program. Based on data from two varicella active surveillance sites, the varice...