The roots of Nardostachys jatamansi have been used as a substitute for valerian in Iranian traditions. Moreover, six species from Valeriana genus such as V. sisymbriifolia grow in Iran which has not been studied yet. We aimed to study of antioxidant effect of Valeriana officinalis, Nardostachys jatamansi and Valeriana sisymbriifolia and comparing their content of valerenic acid and valepotriate...

Valerian root (Valeriana officinalis) is a popular and widely available herbal supplement, primarily used to treat insomnia and anxiety. Until recently, its mechanism of action has remained unknown. Neurobiological research has begun to show that the herb, with its active valerenic acid, interacts with the GABA(A)-ergic system, a mechanism of action similar to the benzodiazepine drugs. This ser...

In this work, samples of the medicinal plants: Boldo (Peumus boldus), Castanha da Índia (Aesculus hippocastanum), Chá Verde (Camelia sinensis), Erva Cidreira (Melissa officinalis), Espinheira Santa (Maytenus ilicifolia), Guaraná (Paullinia cupana), Maracujá (Passiflora sp.), Mulungu (Erythrina velutina), Sene (Cassia angustifolia) and Valeriana (Valeriana officinalis) were evaluated BY using th...

This study was conducted on experimental field at Garmsar zone in Iran during 2010 – 2011 in order to Evaluation of medicinal plant valerian (Valeriana officinalis L.) essential oil compositions cultivated at Garmsar zone in Iran. Sowing date was 20 September and planting densitiy was 80000 plant ha. The volatile constituents of the root part of cultivated Valeriana officinalis were isolated by...

Using plants in therapy originates from far past. The skill of treating with plants has been developed in all nations and is now preserved, more or less, as traditional or popular therapy, commonly named popular medicine. Valeriana officinalis, which has been successfully used in traditional therapy, is accepted and represents an important medicinal raw material in contemporary medicine. Consid...

Parkinson's disease (PD) is one of the most common neurodegenerative disorders. A theoretical approach of our previous experiments reporting the cytoprotective effects of the Valeriana officinalis compounds extract for PD is suggested. In addiction to considering the PD as a result of mitochondrial metabolic imbalance and oxidative stress, such as in our previous in vitro model of rotenone, in ...

Valeriana glechomifolia Meyer is a small herb 5}10 cm high, growing in South Brazil. The plant was collected in April, 1998 in Sa8 o JoseH dos Ausentes, RS, Brazil and identi"ed by M. Sobral (Curso de PoH s-Graduac7 a8 o em Cie( ncias Farmace( uticas da Universidade Federal do Rio Grande do Sul, Brazil). Voucher specimens (M. Sobral, 7733) are kept in the Herbarium of the Universidade Federal d...

Valeriana officinalis is one of the most popular medicinal plants commonly used as a sedative and sleep aid. It is suggested that its pharmacologically active compounds derived from the root may modulate the CYP3A4 gene expression by activation of pregnane X receptor (PXR) or constitutive androstane receptor (CAR) and lead to pharmacokinetic herb-drug interactions. The aim of the study was to d...

The paper presents results obtained within analysis of aqueous preparations obtained from the herbal drugs, (APHD) which are available in pharmacy as mass produced drugs. In particular, the following drugs were analyzed: CYNAROFIT, L'ALIAFIT, Tinctura belladonnae, Tinctura gentianae, Tinctura chinae a Tinctura valerianae made by Calendula, j.s.c.--Slovakia and Tinctura valerianae made by IVAX-C...

Three new germacrane-type sesquiterpenoids, volvalerenal F (1), volvalerenal G (2) and volvalerenic acid D (3), along with five known compounds 4-8, were isolated from the CHCl₃ soluble partition of the ethanol extract of Valeriana officinalis var. latiofolia. The structures of the new compounds were determined on the basis of spectroscopic evidence, including their 1D- and 2D-NMR spectra, as w...