Vaginal small interfering RNA (siRNA) delivery provides a promising strategy for the prevention and treatment of vaginal diseases. However, the densely cross-linked mucus layer on the vaginal wall severely restricts nanoparticle-mediated siRNA delivery to the vaginal epithelium. In order to overcome this barrier and enhance vaginal mucus penetration, we prepared spray-dried powders containing s...

The objective of this work was to obtain prevalence estimates of cloudy vaginal mucus in artificially inseminated Holstein cows raised under intense heat, in order to assess the effect of meteorological conditions on its occurrence during estrus and to determine its effect on conception rate. In a first study, an association was established between the occurrence of cloudy vaginal mucus during ...

the present work was carried out to study the variation in biochemical properties of cervico-vaginal mucus of pregnant and non pregnant animals which could help to design suitable tool in future for early pregnancy diagnosis in buffaloes. cervico-vaginal mucus samples were obtained from 30 buffaloes (12 pregnant and 18 non pregnant) and some biochemical parameters were compared. means of ph, so...

The present work was carried out to study the variation in biochemical properties of cervico-vaginal mucus of pregnant and non pregnant animals which could help to design suitable tool in future for early pregnancy diagnosis in buffaloes. Cervico-vaginal mucus samples were obtained from 30 buffaloes (12 pregnant and 18 non pregnant) and some biochemical parameters were compared. Means of pH, so...

Unexplained infertility diagnosis is made in the presence of a normal semen analysis when tubal patency and normal ovulatory function are established. Among several potential causes, unexplained infertility could be attributed to vaginal pH and cervical mucus abnormalities. Although the vaginal canal and the cervix generally function as effective barriers to sperm, and although the production o...

in order to study the signs of œstrus in the west african dwarf goat, 28 non pregnant females younger than 24 months of age were used. most of them (94.7%) had waggled the tail during heat. the frequency of micturition was higher in the presence of the male. the swelling of the vulva was observed in 68.4% of goats in heat. the cervico-vaginal mucus was significantly (p≤0.05) abundant and elasti...

Human tissue kallikrein-related peptidases (KLKs) are 15 hormonally regulated genes on chromosome 19q13.4 encoding secreted serine proteases. Many KLKs are expressed throughout the female reproductive system and found in cervico-vaginal fluid (CVF). Immunohistochemistry was performed to determine KLK localization in the female reproductive system (fallopian tube, endometrium, cervix and vagina ...

Small hand-held microscopes have been developed for self-observation of salivary ferning patterns to detect the fertile time of a woman's menstrual cycle. The purpose of this study was to evaluate one such microscope, the Lady Free Biotester, by comparing it with the self-observation of cervical-vaginal mucus and with the self-detection of luteinizing hormone (LH) in the urine. Twelve natural f...

Pellegrin A.O., Miranda K.L., Figueiredo J.F., Barbosa E.F. & Lage A.P. 2011. The use of enzyme-linked immunosorbent assay and immunoblotting for the detection of Campylobacter fetus immunoglobulins in the cervico-vaginal mucus of female cattle. Pesquisa Veterinária Brasileira 31(3):247-254. Embrapa Pantanal, Rua 21 de Setembro 1880, Corumbá, MS 79320-900, Brazil. E-mail: [email protected]...

In order to study the signs of œstrus in the West African Dwarf goat, 28 non pregnant females younger than 24 months of age were used. Most of them (94.7%) had waggled the tail during heat. The frequency of micturition was higher in the presence of the male. The swelling of the vulva was observed in 68.4% of goats in heat. The cervico-vaginal mucus was significantly (P≤0.05) abundant and elasti...