introduction: aim was to study the influence of serum testosterone and urinary citrate on the formation of urinary stones in men and women, and to apply the findings for preventing urolithiasis. methods: we studied 200 patients (100 were men and 100 women) who had referred to the urology clinic at imam khomeini hospital and seda sima eswl center. in both groups, 50 were stone formers and 50 wer...

background: potassium citrate (k‑cit) is one of the medications widely used in patients with urolithiasis. however, in some cases with calcium oxalate (caox) urolithiasis, the significant response to alkaline therapy with k‑cit alone does not occur. there is scarce published data on the effect of magnesium chloride (mg‑cl2) on urolithiasis in pediatric patients. this study aimed to evaluate the...

Male Wistar-strain rats which had been fed a glycolic-acid diet developed severe nephrocalcinosis with urinary calculi within 4 weeks. Rats fed the same diet with citrate salts added had, however, either slight or no nephrocalcinosis without any stones in the urinary system. Nephrocalcinosis intermediate between those in the citrate groups and the glycolic-acid group, with some urinary calculi,...

OBJECTIVE To identify the difference in urinary citrate excretion between Stone Formers (SF) and Healthy Volunteers (HV) as a metabolic risk factor, that predisposes to urinary stone formation and to compare levels of urinary citrate in (HV) with reference values. METHODS The 24 hours urinary citrate was evaluated in 40 patients treated for renal citrate and declared stone free, and 40 age ma...

First, the urinary metabolic profiling by gas chromatography-mass spectrometry (GC-MS), was performed to compare ten cadmium (Cd) toxicosis cases from a Cd-polluted area in Mae Sot (Thailand) with gender-matched healthy controls. Orthogonal partial list square-discrimination analysis was used to identify new biomarker candidates in highly Cd exposed toxicosis cases with remarkable renal tubular...

We evaluated the crystallization of calcium oxalate (CaOx) in undiluted urine, collected 3 hours after intake of a test meal by healthy males. In two experiments in vitro, either the total citrate concentration was increased (urine A) or the pH was elevated (urine B). In addition, in three clinical trials, the bioequivalence of orally taken potassium citrate (PC) and potassium-sodium citrate (P...

background: urinary oxalate and citrate are the keyfactors in caox urolithiasis of cats and gamma glutamyltransferase is a good test for assessment of kidney damage.favorable effects of cynodon dactylon on calcium oxalate stoneformation have recently been proved in rats. objectives: thepresent study was designed to investigate the alteration ofurinary oxalate, citrate, and ggt after administrat...

BACKGROUND: Urinary oxalate and citrate are the keyfactors in caox urolithiasis of cats and Gamma GlutamylTransferase is a good test for assessment of kidney damage.Favorable effects of Cynodon dactylon on calcium oxalate stoneformation have recently been proved in rats. OBJECTIVES: Thepresent study was designed to investigate the alteration ofurinary oxalate, citrate, and GGT after administrat...

Background: Nephrolithiasis is a common disorder with high rate of prevalence and recurrence without treatment. Urinary citrates, among others are important inhibitors of stone formation. The mean urinary citrate excretion is 640mg/d in healthy individuals. Hypocitraturia is a common metabolic abnormality detected in stone formers. Aim: To determine frequency of hypocitraturia among patients wi...