manfaluti is one of egyptian authors in 20th century who paid most attention to social and mental issues of egypt nation. thus perhaps it is better to introduce manfauti as a scholar rather than literary man so that his readers have been interested in his works because of their social subjects since long time ago. some believe that manfaluti's works contain no technical elements. hence, th...

Background Posttranscriptional mechanisms of gene regulation, particularly those affecting mRNA stability, are emerging as critical effectors of gene expression changes. Although the mechanisms determining mRNA turnover are poorly understood, they are generally believed to involve RNAbinding proteins recognizing specific RNA sequences. Best characterized among the RNA sequences that influence m...

I want to tell you a story. This is a story about stories. As in any good story, we’re going to wander down a few storied paths. One of the paths leads back to 3 award-winning stories.* Remarkable stories by remarkable physicians who take seriously the power of stories—who have written powerful stories. Another path is about the importance of stories for human health and well-being from the per...

The aim of this paper is to analyse the role exerted by X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and haplotypes in increasing breast cancer risk and in modulating radiotherapy-induced adverse reactions. An Italian cohort of breast cancer patients and a matching group of healthy controls were genotyped for XRCC1-77T>C, Arg194Trp and Arg399Gln polymorphisms. Our data...

Technology, especially multimedia technology, is changing the way we tell stories. We are all familiar with letters, articles, and books, but new Internet technology has led to two novel forms of storytelling that we call micro stories and mega stories. Micro stories are the short bits of text and images that we use to tell our friends about our daily life, what we had for lunch, and the funny ...

The tick-borne encephalitis virus (TBEV) strains have been isolated from unfed adult ticks Ixodes persulcatus Schulze in Novosibirsk region (South-Western Siberia, Russia) beginning from 1980 till 2006. The TBEV 3'-untraslated region (3'UTR) variable fragment was amplified with primers corresponding to conserved flanking areas. The RT-PCR product lengths varied in range from 100 to 400 bp. Comp...

Major histocompatibility complex class II (MHCII) molecules are heterodimeric surface proteins involved in the presentation of exogenous antigens during the adaptive immune response. We demonstrate the existence of a fine level of regulation, coupling the transcription and processing of mRNAs encoding α and β chains of MHCII molecules, mediated through binding of their Untraslated Regions (UTRs...