introduction: the selection of   optimal treatment of obstructive nephrouropathy requires information about the functional status of each kidney. nuclear renal scanning objectively measure differential renal function, multiple studies have demonstrated the role of assessment of renal perfusion and gfr with triphasic ct. the aim of this study is to assess the role of ct based on renal parenchyma...

Introduction: The selection of   optimal treatment of obstructive nephrouropathy requires information about the functional status of each kidney. Nuclear renal scanning objectively measure differential renal function, multiple studies have demonstrated the role of assessment of renal perfusion and GFR with triphasic CT. The aim of this study is to assess the role of CT based on renal parenchyma...

uretero pelvic junction (upj) obstruction is a common cause of hydronephrosis in infants. the frequent use of fetal ultrasound is allowing early (prenatal) diagnosis of numerous uropathies previously delayed until the child either became symptomatic or had a palpable mass. newborn with severe obstruction often has marked improvement following correction, therefore, early diagnosis and operation...

Background: Variation in Renal restive index (RI) values measured using duplex Doppler ultrasonography has been shown to correlate with the degree of renal impairment in acute renal obstruction ,diabetic and hypertensive nephropathy patients. Aims and objectives: The primary objective of this study was to determine whether the intrarenal resistive index can be used as a predictor of progression...

An increasing number of comprehensive genetic fate mapping studies have demonstrated that pericytes are the main progenitors renal scar-forming myofibroblasts, and contribute in poor repair acute kidney injury progression to chronic disease. Following unilateral ureteral obstruction, injured epithelial cells primarily secreted TGF-β1, which could then trigger pericyte-myofibroblast transition (...

Obstructive uropathy is defined as structural obstruction to urine flow along the urinary tract. It can lead to dilatation of renal pelvis and calyces. (1). However renal pelvis can be dilated without obstruction. Therefore hydronephrosis and dilated renal pelvis are not synonymous terms. The damage to renal tissue caused by these conditions often leads to obstructive nephropathy contributing t...

We investigated the renal response to direct renal nerve stimulation, 2 weeks following reversal of 24-h unilateral (left) ureteric obstruction. Renal nerve stimulation caused a 13-15 % fall in renal blood flow, in 4 groups of anesthetized rats following ureteric obstruction (n=9) or a sham operation (n=7) both with (n=9) and without (n=7) treatment with the mixed ET(A/B) receptor antagonist, b...

We investigated the renal response to direct renal nerve stimulation, 2 weeks following reversal of 24-hr unilateral (left) ureteric obstruction. Renal nerve stimulation caused a 13-15% fall in renal blood flow, in 4 groups of anaesthetised rats following ureteric obstruction (n=9) or a sham operation (n=7) both with (n=9) and without (n=7) treatment with the mixed ETA/B receptor antagonist, bo...