Journal:
:iranian journal of pharmaceutical research
0
omid gholami pharmacology department, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran.
mahmood jeddi-tehrani monoclonal antibody research center, avicenna research institute, acecr, tehran, ir iran.
mehrdad iranshahi biotechnology research center and school of pharmacy, mashhad university of medical sciences, mashhad, ir iran.
amir hassan zarnani nanobiotechnology research center, avicenna research institute, acecr, tehran, ir iran.
seyed ali ziai pharmacology department, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran.
umbelliprenin is a prenylated compound, which belongs to the class of sesquiterpene coumarins. it is extracted from dried roots of ferula szwitsiana collected from the mountains of golestan forest (golestan province, north of iran). induction of apoptosis in jurkat t-cll cells has been previously shown. in this study, effect of umbelliprenin on proapoptotic caspases (caspase-8 and -9) and antia...