abstract background: pressure ulcer is one of the main concerns of nurses in medical centers around the world, which, if untreated, causes irreparable problems for patients. in recent years, nitric oxide (no) has been proposed as an effective method for wound healing. this study was conducted to determine the effect of nitric oxide on pressure ulcer healing. materials and methods: in this clini...

background previous reports have shown that quince seed might have some healing effects on skin ulcers in rabbits. objectives to assess the potential healing effect of quince seed cream on human skin ulcers. patients and methods the present study was a double-blind, randomized, controlled trial. fifty patients with skin ulcer caused by disposable biopsy punch 5 mm were allocated in two groups (...

abstract background: pressure ulcers’ treatment imposes a considerable cost on health system and patients. electrical stimulation has already been introduced as an effective method for promoting wound healing. this study was conducted to determine the impact of interferential current (if) on healing of pressure ulcers (grade1 and 2). materials and methods: in this clinical trial, 23 patients (1...

case presentation the patient was a 45-year-old male with t8 complete paraplegia; he had developed severe pressure ulcer. the authors used lllt as a complementary treatment. they used 980 nm, continuous 6 j/cm2 for margins and 655 nm, continuous 1.8 j/cm2 for bed of the ulcer, along with intravascular laser therapy. after 24 sessions of lllt and z-plasty surgery, the ulcer healed completely. co...

The healing of gastric ulcer is a complicated process that involves the proliferation of epithelial and endothelial cells and the concerted actions of a wide range of growth factors. Prostaglandins play an important role in ulcer healing. Expression of cyclooxygenase-2 (COX-2) is markedly upregulated around the margins of gastric ulcers and its inhibition leads to a delay of ulcer healing. Seve...

Evidence-based ulcer care guidelines detail optimal components of care for treatment of ulcers of different etiologies. We investigated the impact of providing specific evidence-based ulcer treatment components on healing outcomes for lower limb ulcers (LLU) among veterans in the Pacific Northwest. Components of evidence-based ulcer care for venous, arterial, diabetic foot ulcers/neuropathic ul...

Compression bandaging achieved a higher proportion of complete ulcer healing, reduced ulcer size, and improved psychosocial outcomes in venous ulcer patients. The four-layer bandaging and short-stretch bandaging systems achieved a similar effect on both ulcer healing and other psychosocial outcome measures. Effect of compression bandaging on wound healing and psychosocial outcomes in older peop...

Delayed gastric ulcer healing is a well recognized problem associated with the use of cyclooxygenase (COX) inhibitors. In contrast, NO-releasing COX inhibitors do not interfere with ulcer healing. These divergent effects may in part be due to differences in their effects on platelets, which are known to influence ulcer healing. Therefore, we compared the effects of a nonselective COX inhibitor ...

A multiple linear regression analysis was carried out on 75 inpatients with gastric ulcer. In order to elucidate the effects of various factors - endoscopic and roentgenological findings, age, sex, medical history, and drugs such as antacids, anticholinergics or both - on the healing rate, these factors were compared between those with ulcer which healed within eight weeks after treatment and t...