نتایج جستجو برای: u33

تعداد نتایج: 39  

Journal: :RNA 1999
S S Ashraf R Guenther P F Agris

Binding of transfer RNA (tRNA) to the ribosome involves crucial tRNA-ribosomal RNA (rRNA) interactions. To better understand these interactions, U33-substituted yeast tRNA(Phe) anticodon stem and loop domains (ASLs) were used as probes of anticodon orientation on the ribosome. Orientation of the anticodon in the ribosomal P-site was assessed with a quantitative chemical footprinting method in w...

Journal: :Cancer research 2015
Aaron M LeBeau Natalia Sevillano Kate Markham Michael B Winter Stephanie T Murphy Daniel R Hostetter James West Henry Lowman Charles S Craik Henry F VanBrocklin

The increased proteolytic activity of membrane-bound and secreted proteases on the surface of cancer cells and in the transformed stroma is a common characteristic of aggressive metastatic prostate cancer. We describe here the development of an active site-specific probe for detecting a secreted peritumoral protease expressed by cancer cells and the surrounding tumor microenvironment. Using a h...

Journal: :Nucleic Acids Research 2005
Javier Cabello-Villegas Edward P. Nikonowicz

Nucleoside base modifications can alter the structures and dynamics of RNA molecules and are important in tRNAs for maintaining translational fidelity and efficiency. The unmodified anticodon stem-loop from Escherichia coli tRNA(Phe) forms a trinucleotide loop in solution, but Mg2+ and dimethylallyl modification of A37 N6 destabilize the loop-proximal base pairs and increase the mobility of the...

1999
Djordje Krstic

A special kind of shape algebra is defined for concurrent computations with shapes and their boundaries, together with related shape grammars. Some new types of shape grammar are defined and classified. Table 1. Hierarchy of shape algebras. U00 U01 U02 U03 U11 U12 U13 U22 U23 U33 DOI:10.1068/b2681

2006
Rudi Stouffs Ramesh Krishnamurti

This paper continues with the subject matter that we introduced previously (Krishnamurti and Stouffs, 2004). Here, we describe algorithms for classifying the boundary of a shape with respect to another, coequal, shape and for constructing the description of a shape given parts of the boundary that make up the shape. Specifically, algorithms for classification and construction of shapes in U23 (...

Journal: :RNA 2002
Pamela F Crain Juan D Alfonzo Jef Rozenski Stephen T Kapushoc James A McCloskey Larry Simpson

Editing of tRNA has a wide phylogenetic distribution among eukaryotes and in some cases serves to expand the decoding capacity of the target tRNA. We previously described C-to-U editing of the wobble position of the imported tRNA(Trp) in Leishmania mitochondria, which is essential for decoding UGA codons as tryptophan. Here we show the complete set of nucleotide modifications in the anticodon a...

Journal: :Nucleic acids research 1992
A Przykorska C el Adlouni G Keith J W Szarkowski G Dirheimer

A single-strand-specific nuclease from rye germ (Rn nuclease I) was characterized as a tool for secondary and tertiary structure investigation of RNAs. To test the procedure, yeast tRNA(Phe) and tRNA(Asp) for which the tertiary structures are known, as well as the 3'-half of tRNA(Asp) were used as substrates. In tRNA(Phe) the nuclease introduced main primary cuts at positions U33 and A35 of the...

2014
G. Machicoane N. Bultman L. T. Sun

The Facility for Rare Isotope Beams (FRIB) at Michigan State University will provide intense beams of rare isotopes for research in nuclear physics, nuclear astrophysics and study of fundamental interactions. A Superconducting linac will accelerate the primary beam to energies beyond 200 Mev/u and is designed to reach a maximum beam power close to 400kW on the fragmentation target. In the case ...

Journal: :RNA 2001
P Auffinger E Westhof

Anticodon hairpins are structural motifs with contradictory functions. The recognition by aminoacyl synthetases implies extended interactions with the anticodon base triplet and thus, usually, an unfolding of the anticodon loop. The recognition by the ribosome and cognate interaction with a mRNA codon implies, on the other hand, the formation of a mini-helix with a canonical anticodon hairpin s...

2001
PASCAL AUFFINGER ERIC WESTHOF

Anticodon hairpins are structural motifs with contradictory functions. The recognition by aminoacyl synthetases implies extended interactions with the anticodon base triplet and thus, usually, an unfolding of the anticodon loop. The recognition by the ribosome and cognate interaction with a mRNA codon implies, on the other hand, the formation of a mini-helix with a canonical anticodon hairpin s...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید