Twenty Nail Dystrophy (TND) is a rare acquired idiopathic nail dystrophy characterized by excess longitudinal ridging, distal notching, splitting, loss of nail luster and thinning of nail plates that may affect 1 to 20 nails. It occurs as a common manifestation of various dermatoses affecting the nail unit like lichen planus, psoriasis, atopic dermatitis, onychomycosis, vitiligo and alopecia ar...

BACKGROUND/AIMS The term trachyonychia, also known as twenty-nail dystrophy, is used to describe thin, brittle nails with excessive longitudinal ridging. The term twenty-nail dystrophy has been incorrectly applied to other conditions that can affect all twenty nails. Therefore, we have conducted a comprehensive review of the clinical features of trachyonychia and have included a discussion rega...

Twenty Nail Dystrophy (TND) is a rare acquired idiopathic nail dystrophy characterized by excess longitudinal ridging, distal notching, splitting, loss of nail luster and thinning of nail plates that may affect 1 to 20 nails. It occurs as a common manifestation of various dermatoses affecting the nail unit like lichen planus, psoriasis, atopic dermatitis, onychomycosis, vitiligo and alopecia ar...

Congenital alopecia universalis is one of the rarest anomaly which involves skin and appendages. The inheritance pattern can be autosomal recessive, X-linked recessive, or autosomal dominant. However, the most common is autosomal recessive form and it is the most severe phenotype. Twenty-nail dystrophy refers to the condition in which all the twenty nails are affected in the form of excessive r...

Candida parapsilosis is an emerging fungal pathogen that was once thought to be solely a colonizing organism. C. parapsilosis is increasingly becoming reported as the most common Candida species that causes onychomycosis. Clinical findings include typically severe dystrophy of the nail fold and plate as well as thickening and fragmentation of the plate, particularly in the distal plate. We pres...

We hereby report a 79-year-old Iranian man presenting with nail dystrophy and subsequent development of purpuric and ecchymotic plaques, hemorrhagic bullae, and infiltrated papules on the head, neck and trunk. Histological examination of the gingiva, bone marrow aspiration, and biopsy confirmed the diagnosis of primary systemic amyloidosis. In this case, nail dystrophy was the presenting sign o...