a discrete mibi avid lung lesion was found in cinematic views of myocardial perfusion imaging (mpi) of a 59 year-old woman. interestingly, the abnormal uptake in the lung was detectable only in the rest phase images and not in the images acquired in the stress phase. mpi was performed for pre-operation cardiac risk assessment before correction surgery for spinal canal stenosis.  she had no past...

background: cardiac risk assessment with myocardial perfusion imaging (mpi) is a common practice for some elderly breast cancer patients who are candidates for operation. in rare cases the tumor may become visible in the images. case presentation: this is the report of a case with a huge slow-growing breast tumor suspicious for malignancy and presenting with methoxy-isobutyl-isonitrile (mibi) u...

objective(s): considering the fact that the standardized uptake value (suv) of a normal lung tissue is expressed as x±sd, x+3×sd could be considered as the threshold value to outline the internal tumor volume (itv) of a lung neoplasm. methods: three hollow models were filled with 55.0 kbq/ml fluorine18- fluorodeoxyglucose (18f-fdg) to represent tumors. the models were fixed to a barrel filled w...

Objectives: The monitoring of cancer treatment response to chemotherapy is considered an essential strategy for follow-up of patients. The aim of this study was to evaluate the use of 99mTc-glucarate as a radiotracer for in vivo quantification and visualization of necrotic area and therapeutic effect of paclitaxel in ovarian cancer xenografted nude mice. Materials and Methods: After implantatio...

67Gallium-bleomycin complex (67Ga-BLM) was prepared using Thakour method. Radio-thin-layer-chromatography of prepared complex showed A2 and B2 radiopeaks with Rf at 0.7 and 0.4 respectively with a purity of above % 95. Tissue uptake of 67Ga-BLM and 67GaCl3 in twelve tissues including tumor, blood, liver, lung, spleen, muscle, skin, heart, kidney, colon, colon content ,bladder and the tota...

objective(s): the present study was conducted to examine whether the standardized uptake value (suv) may be affected by the spatial position of a lesion in the radial direction on positron emission tomography (pet) images, obtained via two methods based on time-of-flight (tof) reconstruction and point spread function (psf). methods: a cylinder phantom with the sphere (30mm diameter), located in...

background: dendritic cells (dcs) are professional antigen presenting cells (apcs), and there is considerable interest in their application as a cellular adjuvant for cancer immunotherapy.  previous studies indirectly demonstrated that dcs were able to take up tumor lysate (crude soluble tumor antigens) and also cross-present tumor associated antigens (taa) which elicits anti-tumor immune respo...

Background: Dendritic cells (DCs) are professional antigen presenting cells (APCs), and there is considerable interest in their application as a cellular adjuvant for cancer immunotherapy.  Previous studies indirectly demonstrated that DCs were able to take up tumor lysate (crude soluble tumor antigens) and also cross-present tumor associated antigens (TAA) which elicits anti-tumor immune respo...

Herein we report the possibility of using green and red emitting silica-coated cadmium selenide (CdSe) quantum dots (QDs) for remarkable stem and cancer cellular imaging, efficient cellular uptake and fluorescence imaging of semi and ultra-thin sections of tumor for in vivo tumor targeted imaging applications. The comparative studies of high contrast cellular imaging behaviours of the silica-co...