extra renal extra cranial malignant rhobdoid tumors (mrt) are rare, frequently lethal and affect mostly children. no definite treatment has been made and the role of radiation therapy is poorly defined. this report explains a 14 year old girl with mrt in her neck soft tissue. she is alive with no evidence of disease 18 months after diagnosis. through the experience with this case, we suggested ...

In this paper, we have proposed and analyzed a mathematical model for the study of interaction between tumor cells and oncolytic viruses. The model is analyzed using stability theory of differential equations.

background: cancer immunotherapy attempts to stimulate the immune system to reject and destroy tumors and is one of the cancer treatment strategies. recently, interluekin36 (il36) has been used as immunotherapeutic agents in cancer gene therapy. present study investigated that the il36 gene therapy effects on the regression of tumor masses in mouse model. aim of this study is determination of t...

background and objective: p53 is a suppressive gene that plays a key role in dna repair and apoptosis. the purpose of this study was to investigate the effect of p53 protein over-expression and some clinicopathological factors on the esophageal squamous cell carcinoma (scc) response to neoadjuvant chemoradiotherapy. patients and methods: in this retrospective cohort study, 44 patients with loca...

background: overexpression of rad51 protein in many tumor cells has been proven to increase radioresistance and can be related to the resistance of chemosensitivity of tumor cells. this preliminary study was conducted to determine the relationship between the rad51 expression level in nasopharyngeal carcinoma and the response of the treatment based on the measurement of the tumor reduction. met...

A growing area of research is focused on cancer therapy, and new therapeutic approaches are welcomed. Mesenchymal stem cell (MSC)-based gene therapy is a promising strategy in oncology. Intrinsic tropism and migration to tumor microenvironment with off lights are attractive features of this type of cell carrier. In this way, suicide genes have also found a good platform for better performance a...

radiation therapy is considered as one of the main methods in cancer treatment. in this method, determination of exact location and geometric properties of tumor is necessary for treatment planning that leads to increased accuracy and output of treatment and reduction of healthy tissue dose. for this purpose, the aim of the present study has been physiological transmission of gallium as a pharm...

Background: Overexpression of Rad51 protein in many tumor cells has been proven to increase radioresistance and can be related to the resistance of chemosensitivity of tumor cells. This preliminary study was conducted to determine the relationship between the Rad51 expression level in nasopharyngeal carcinoma and the response of the treatment based on the measurement o...

Drug Free Tumor Theranostics In article number 2205165, Tymish Y. Ohulchanskyy and co-authors introduce hemoglobin nanocrystals for drug free, synergistic selective theranostics of colon cancer. After intravenous (i.v.) injection, these target tumor react with tumor-specific H2S H2O to enable magnetic resonance imaging guided photothermal therapy produce •OH chemodynamic therapy.