background: in recent years, epidemiologic and laboratory studies have implied that vitamin d deficiency has a role in the pathogenesis of breast cancer. it has shown that vitamin d can prevent tumor progression induced by carcinogens and inhibit the carcinogenic effects of high fat diet on breast tissue and growth of tumor cells. this study aimed to evaluate serum 25-hydroxyvitamin d level and...

background : the intent of this study was to audit and evaluate the information content of pathology reports of resected gastric cancer specimens in yazd, iran. methods : all gastric cancer reports of patients from the histopathology laboratories in yazd over a six-year period who referred for adjuvant radiation therapy to shahid ramazanzadeh radiation oncology center were evaluated for their i...

tumor angiogenesis shown by microvessel count (mvc) or microvessel density (mvd), is assessed by several studies as prognostic factor in some types of tumors, and also in colorectal carcinoma. this article is payed to correlation between clincopathologic factors and tumor angiogenesis. in this study, immunohistochemical techniques are used for vascular evaluation in specimens from twenty-nine c...

Background and Aims: An impairment of expression in MLL2 gene involved in histone methylation induces alteration in the methylation patterns at enhancers and causes several cancers including colon cancer. In this study, MLL2 expression was evaluated in North West of Iran. Materials and Methods: To evaluate the MLL2 expression in patients with colon cancer, 25 tumor samples and 25 samples of tu...

background and objectives: rcc is one of the most common genitourinary cancers. accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. p53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle arrests after dna damage and apoptosis. presence of mutated p53 protein in tumors has been rel...

abstract background: gastric cancer is one of the most common cancers in the world especially in iran. there are many genomic and molecular factors that cause gastric cancer to occur. also, many markers that associate with tumor invasiveness have been known.  e-cadherin is a calcium- mediated cell adhesion molecule. in some studies, abnormal expression of e-cadherin has been seen in gastric car...

Background and Objectives: RCC is one of the most common genitourinary cancers. Accurate prediction of prognosis would be valuable for adjuvant trial design, counseling and effectively scheduling follow up visits. P53 is a tumor suppressor gene that expresses a protein that involved in both cell-cycle ar...

  Abstract   Background: Squamous cell carcinoma (SCC) constitutes the main oral malignancy .   Parallel to better understanding of molecular and genetic patterns of tumor behavior, more precise correlation of tumor markers such as Epidermal Growth Factor (EGF) and Laminin-5 are sought to estimate macroscopic and microscopic tumor status .   Methods: We conducted a cross-sectional study collect...