Background: Tumor lysis syndrome caused by widespread tumor cell damage may lead to electrolyte imbalances and express as metabolic disturbance causing clinical abnormalities. Patients and Methods: All patients younger than 16 years with documented malignancy candidate for chemotherapy, in Hamedan province of Iran were enrolled. Results: Out of 69 cancer patients the laboratory form of tumor ...

background: tumor lysis syndrome caused by widespread tumor cell damage may lead to electrolyte imbalances and express as metabolic disturbance causing clinical abnormalities. patients and methods: all patients younger than 16 years with documented malignancy candidate for chemotherapy, in hamedan province of iran were enrolled. results: out of 69 cancer patients the laboratory form of tumor ly...

abstract background tumor lysis syndrome (tls) is an oncologic emergency that results from massive lysis of malignant cells. the incidence of tls depends on the risk factors, such as baseline hyperuricemia, bulky tumor burden, elevated serum ldh, and elevated wbc. the objectives of the present study were to assess frequency of tumor lysis syndrom in children with all in two methods of induction...

background: tumor lysis syndrome (tls) is a major metabolic complication in patients with malignancy after initiation of chemotherapy or spontaneously without treatment. the role of rasburicase (a recombinant urate-oxidase enzyme) in prevention and treatment of tls has been demonstrated in recent years. we aimed to investigate the efficacy of a single dose of rasburicase in reducing the risk of...

a male patient with acute renal failure (arf) due to large b-cell non-hodgkin lymphoma infiltration of kidney is presented. the diagnosis was suspected because of coincidence of arf and tumor lysis syndrome non-responsive to conservative renal therapies. a renal biopsy confirmed diagnosis and appropriate chemotherapy led to complete improvement of renal function.

Abstract Background Tumor Lysis Syndrome (TLS) is an oncologic emergency that results from massive lysis of malignant cells. The incidence of TLS depends on the risk factors, such as baseline hyperuricemia, bulky tumor burden, elevated serum LDH, and elevated WBC. The objectives of the present study were to assess frequency of Tumor Lysis Syndrom in children with ALL in two methods of inducti...

Introduction. Tumor lysis syndrome is an emergency condition requiring prompt recognition and treatment. It?s a consequence of spontaneous or therapy-induced cellular death leading to the release intracellular ions metabolic products purine bases into bloodstream. Pathophysiology. The characteristic derangement comprises hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia. These change...

Early detection of renal dysfunction can help clinicians plan optimal treatment strategies to manage the underlying cause, such as a paraneoplastic syndrome or tumor lysis syndrome. Effective management improve overall clinical outcomes lung cancer patient.