background: study in design to incorporate accelerated proliferation correction factors into linearquadratic and multiple-component models. materials and methods: accelerated proliferation rate correction factor has been incorporated into the linearquadratic and the multiple component models by applying accelerated exponential cell growth to explain the tumor cell kinetics and estimates proper ...

Introduction: The ultimate goal of radiation treatment planning is to yield a high tumor control probability (TCP) with a low normal tissue complication probability (NTCP). Historically  dose volume histogram (DVH) with only volumetric dose distribution was utilized as a popular tool for plan evaluation  hence present study aimed to compare the radiobiological effectiveness of the cobalt-60 (Co...

Introduction: The aim of this study was to evaluation radiobiological modeling parameters on tumor control probability (TCP) for prostate cancer in three different models. These parameters included α⁄β ratios and cell surviving fraction at 2 Gy (SF2). Materials and Methods: The Poisson, equivalent uniform dose (EUD) and linear quadratic (LQ) models was used as...

Introduction: The high local control rates observed in patients with breast cancer who had been treated by modified radical mastectomy, chemotherapy and chest-wall irradiation using 120 kV X-rays (50 Gy in 25 fractions) motivated us to investigate their observed tumor control probability (TCP) and test a well-established radiobiological TCP model against our data. Mat...

PURPOSE Genetic radiotherapy, the combination of gene therapy and radiation therapy, for cancer treatment is evolving from laboratory studies to clinical trials. Genetic radiotherapy involves the viral infection of cells that change the sensitivity of transduced cells to radiation. Because there is no patient outcome data for genetic radiotherapy, prospective models are needed to determine the ...

Introduction: In 3DCRT the number of therapeutic fields has dramatic impact on treatment results especially in stomach cancer. Traditionally, for radiotherapy of stomach cancer the therapeutic procedure was using two fields (AP- PA or AP Lateral with wedge) to achieve smooth and homogeneous dose distribution in tumor. But nowadays, adding lateral or oblique fields to aforement...