background: tuberculous meningitis (tbm) is a severe form of extra pulmonary tuberculosis with high mortality and morbidity rate in all age group patients specific in adults and children. the incidence and prevalence are not exactly known in iran. in this study, we tried to evaluate the role of rapid diagnosis and to find out the highest risk group patients.  methods:totally, 1783-suspected pa...

tuberculous meningitis (tbm) and acute bacterial meningitis (abm) cause substantial mortality and morbidity in both children and adults. identification of poor prognostic factors at patient's admission could prepare physicians for more aggressive monitoring of patients with meningitis. the objective of this study was to determine the predictive value of neurological features to differentiate ab...

Diagnostic confusion often exists between tuberculous meningitis and other meningoencephalitides. Newer diagnostic tests are unlikely to be available in many countries for some time. This study examines which clinical features and simple laboratory tests can differentiate tuberculous meningitis from other infections. Two hundred and thirty two children (110 tuberculous meningitis, 94 non-tuberc...

1. World Health Organization. Fact Sheet N104. Tuberculosis. March 2004. (Accessed October 1, 2004, at http://www.who.int/ mediacentre/factsheets/fs104/en.) 2. Idem . Global tuberculosis control: Vietnam. WHO report 2004. (Accessed October 1, 2004, at http://www.who.int/tb/publications/ global_report/2004/en/VietNam.pdf.) 3. Rich AR, McCordock HA. The pathogenesis of tuberculous meningitis. Bul...

The value of C reactive protein measurement in the differential diagnosis of meningitis was assessed in a population where tuberculous meningitis is prevalent. C reactive protein was measured serially with a sensitive radioimmunoassay in sera from 31 children with bacterial meningitis, 15 with tuberculous meningitis (6 with miliary tuberculosis), and 28 with viral meningitis. Concentrations of ...

BACKGROUND WHO recommends Xpert MTB/RIF as initial diagnostic testing for tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about 50-70% and culture sensitivity of about 60%. We evaluated the diagnostic performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis. METHODS We prospectively obtained diagnostic cerebrospinal fluid (CSF...

OBJECTIVES To compare the clinical and laboratory features of tuberculous meningitis with bacterial meningitis and to determine if protein glucose ratio in the cerebrospinal fluid can be predictive of the condition. METHODS It was a retrospective descriptive study at the Paediatric Ward of Aga Khan University Hospital, Karachi, for which records of 46 patients with tuberculous meningitis and ...

BACKGROUND In the USA, Mycobacterium tuberculosis infection is more likely to be found in foreign-born individuals, and those co-infected with human immunodeficiency virus (HIV) are more likely to have tuberculous meningitis. The literature is lacking in details about the clinical workup of patients presenting with tuberculous meningitis with encephalopathic features who are co-infected with HI...