leprosy is one of the oldest diseases of the country and may have been brought over to this country from egypt in ancient times. leprosy is mose frequent in the province of tehran, east azarbaijan, guilan and mazandaran (43 per km2) than other part of the country (13-18 per km2).the incidence of leprosy is recorded at 7.7 per thousand and 35.2 per thousand in the southern and northern part of t...

The "racket" lesion is a rare presentation of tuberculoid leprosy, which consists of a thickened nerve branch emerging from a tuberculoid plaque. It results from centripetal damage to cutaneous nerves caused by granuloma formation. We describe a typical case of tuberculoid leprosy presenting as a "racket" lesion. The lesion persisted after treatment with paucibacillary multidrug therapy.

background: langerhans cells are important in the pathogenesis of leprosy.  a recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions.   objective: to investigate a possible relationship between the number of langerhans cells and the histopathologic spectrum of lesions in patients with leprosy.   methods: an immunohistochemical staining for s100 ...

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Manifestations of lepra reaction in cases of tuberculoid leprosy or in individual tuberculoid lesions have not been described as such. Evidence of its occurrence would doubtless be found in the literature if it were searched interpretivelybearing in mind the fact that tuberculoid lesions are usually not recognized for what they are. For example, the peculiar nerve abscess common in India is pro...

Cell migration inhibition of white blood cells in the presence of total protein lepromin (TPL) was studied in ten lepromatous patients, six tuberculoid patients, and ten normal controls; adding normal, tuberculoid, lepromatous, or no serum to the culture medium. Using normal or no serum, lepromatous patients and skin negative controls gave negative reactions, while tuberculoid patients and skin...

In an inquiry about the evolution of tuberculoid leprosy, I wrote in 1936 (7), that I had not seen a typical case of tuberculoid leprosy-characterized clinically by its well-defined lesions, bacteriologically by the absence of bacilli, histologically by tuberculoid structure, and immunologically by a positive reaction to lepromin-undergo transformation to the typical lepromatous condition with ...

Discussion Tuberculoid Hansen’s is a disease occurring in an immunocompetent individual with granulomatous reaction in the tissue. Usually no bacillus is identifiable. Nerve involvement is common with thickening of the nerve and numbness of the corresponding region. Leprosy caused by Mycobacterium leprae is one of the oldest diseases on earth. It has its earliest description in India and China ...