Background: The tuberculin test is widely used to identify tuberculosis infection. Some individuals infected with Mycobacterium tuberculosis may have an initial negative skin test reaction to tuberculin. The two step purified protein derivative skin test can decrease misinterpretation of tuberculin test .This study was aimed at comparing the two- step tuberculin skin test and booster phenomenon...

background: the tuberculin test is widely used to identify tuberculosis infection. some individuals infected with mycobacterium tuberculosis may have an initial negative skin test reaction to tuberculin. the two step purified protein derivative skin test can decrease misinterpretation of tuberculin test .this study was aimed at comparing the two- step tuberculin skin test and booster phenomenon...

OBJECTIVE Recommendations that purified protein derivative (PPD) RT-23 tuberculin should not be kept and used more than 24 to 48 hours after opening are rarely complied with. The aim of this study was to determine whether using PPD RT-23 tuberculin from vials that had been open for a longer time could affect results of tuberculin tests and whether the solution could become contaminated. METHO...

BACKGROUND Tuberculosis remains a serious disease worldwide. Anti-tuberculosis campaigners many times face negative tuberculin skin tests after Bacille Calmette Guérin vaccination. Increasing tuberculin units might be a solution. However, is skin reaction a linear function of tuberculin dose? Are there any side-effects when higher tuberculin doses are administered? CASE PRESENTATION Six simul...

INTRODUCTION Rheumatoid arthritis patients under treatment with anti-TNF-α are at a high risk of developing active tuberculosis, and therefore, screening for latent tuberculosis infection is recommended before anti-TNF-α therapy. OBJECTIVE To compare the tuberculin test and IFNγ production induced by culture filtrate proteins(CFPs) and Mycobacterium tuberculosis-specific CFP-10 antigens in rh...

As we have recently reported (2), in cases of lepromatous leprosy, which almost by defiI1ition are lepromin negative, the administration of BCG causes in some cases an increase in the reactivity to lepromin as well as the usual tuberculin conversions. The following are the data there reported, now slightly revised: One hundred and four lepromatous cases, negative to both tuberculin and lepromin...