Trypanosoma cruzi, a hemoflagellate protozoan (family Trypanosomatidae), is the ethiological agent of Chagas disease, which is affecting 16-18 million people, with more than 100 million exposed to the risk of infection. Higher plants are a potential source of new drugs to improve the treatment of Chagase disease. Until recently, Rutacea, Meliaceae, Simaroubaceae and Burceraceae families have be...

background: the study evaluated qualitative pcr, primers 121-122 as a tool to follow up evolution parasite load of trypanosoma cruzi . methods: the study was conducted at the state university of maringa, in 2015. step 1, dilutions 1/10 were performed from t. cruzi -y strain to obtain preparations of 50,000-0.05 parasites/ml from which dna were extracted, quantified, and amplified. step 2, the e...

Trypanosoma cruzi, a hemoflagellate protozoan (family Trypanosomatidae), is the ethiological agent of Chagas disease, which is affecting 16-18 million people, with more than 100 million exposed to the risk of infection. Higher plants are a potential source of new drugs to improve the treatment of Chagase disease. Until recently, Rutacea, Meliaceae, Simaroubaceae and Burceraceae families have be...

The anti-Trypanosoma cruzi activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of Acmella bellidioides, Aspilia silphioides, Viguiera tuberosa, Calyptocarpus biaristatus, Hyalis argentea, Helenium radiatum, Gaillardia megapotamica, Verbesina subcordata, Gymnocoronis spilanthoides, Viguiera anchusaefolia, Thelesperma megapotamicum, Ze...

The anti-Trypanosoma cruzi activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of Acmella bellidioides, Aspilia silphioides, Viguiera tuberosa, Calyptocarpus biaristatus, Hyalis argentea, Helenium radiatum, Gaillardia megapotamica, Verbesina subcordata, Gymnocoronis spilanthoides, Viguiera anchusaefolia, Thelesperma megapotamicum, Ze...

BI-128.De Souza W 1984. Cell biology of Trypanosoma cruzi.Int Rev Cytol 86: 197-285. Engel JC, Doyle PS, Palmer J, Hsieh I, Bainton DF,McKerrow JH 1998. Cysteine protease inhibitorsalter Golgi complex ultrastructure and function in Trypanosoma cruzi. J Cell Sci 111: 597-606.Figueiredo RCBQ, Soares MJ 1996. Low temperatureinhibits the uptake of transferrin-gold complexes ...

Abstract Herein we characterize Trypanosoma cruzi infections from blood and CSF samples in a case series of people with HIV Chagas disease. We identify different infecting T. populations highlighting qPCR usefulness for disease reactivation diagnosis evaluation treatment response.

Chagas disease is caused by the protozoan Trypanosoma cruzi. Seven lineages have been identified based on different molecular markers, namely TcI, TcII, TcIII, TcIV, TcV, TcVI, and TcBat. Dogs play role of epidemiological sentinels being domestic reservoirs T. The aim current study was to report first case CD in a dog Manaus, Amazonas, Brazil, infected with cruzi DTU TcIV. We hope our encourage...

Members of the subfamily Triatominae, family Reduviidae, comprise a large number of insect species of which some are vectors of Trypanosoma cruzi, the causative agent of Chagas' disease. This article outlines research on the process of transformation and the dynamics of developmental stages of Trypanosoma cruzi in the triatomine insect hosts. Special attention is given to the interactions of pa...

Phytochemical investigation of a dichloromethane-methanol (1:1) extract of the fruit pericarp of Omphalocarpum procerum which exhibited antiplasmodial activity during preliminary screening led to the isolation of the new fatty ester triterpenoid 3β-hexadecanoyloxy-28-hydroxyolean-12-en-11-one (1), together with five known compounds 2-6. The structure of the new compound as well as those of the ...