this study focused on triple-negative breast cancer (tnbc) that is characterized by the lack of expression of estrogen receptor (er), progesterone receptor (pr), and human epidermal growth factor receptor 2 (her-2). the primary goal of this study was to describe the relation between triple-negative receptor status and survival. this is the first study about triple-negative breast cancer in our ...

context triple negative breast cancer (tnbc) is a heterogeneous group of diseases that is negative for esterogen receptor (er) progesteron receptor (pr) and human epidermal growth factor receptor 2 (her2). this type of breast cancer is typically high-grade carcinomas, although low-grade tumors occur. the aim of this review is to focus on molecular classification and features, prognostic markers...

Triple negative breast cancer (TNBC): challenges and solutions via the immune cells TNBC is one of the most complicated types of breast cancer to treat. It is generally diagnosed based on the absence of three receptors: estrogen, progesterone, and human epidermal growth factor receptor 2 (HER2) and is thus defined as a triple negative. TNBC is often more aggressive with lower survival rates...

background : breast cancer is one of the most frequent malignancies among iranian women. triple-negative breast cancer (tnbc) is referred to a type of breast cancer which three biomarkers of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (her2), are negative. materials and methods: in this case control study, immunohistopathologic data of patients with tn...

Introduction: Triple-negative breast cancer (TNBC) is a type of breast cancer that is negative for estrogen receptor, progesterone receptor, and HER2. This study aimed to evaluate the clinical outcomes and short-term prognosis of this type of cancer compared with other subtypes of breast cancer. Methods: A cross-sectional study was conducted on 108 women with invasive breast cancer. The patie...

background : triple-negative breast cancers (tnbc) are defined as breast cancers with lack of estrogen and progesterone receptors and no overexpression of human epidermal growth factor receptor 2 (her2). this study was performed to determine the frequency and pathologic features of tnbc in iranian patients. subjects and methods: this cross-sectional study was performed on patients with breast c...

INTRODUCTION Breast cancer is the second most common cancer worldwide (1.3 million cases, 10.9%) and ranks 5 th as cause of death from cancer overall (458,000 cases, 6.1%). Triple-negative breast cancer (TNBC) is a subtype of breast cancer with characteristic biological and pathological features. Among the subgroups of breast cancer, triple negative cancer is particularly feared because it is a...

BACKGROUND Prognostication of breast cancer using clinico-pathologic variables, although useful, remains imperfect. Recent research has focused on finding new markers of prognosis using gene expression profiling. Panels of proteins assessed by immunohistochemistry might also be useful in this regard. This study focused on Bcl-2 protein expression in triple-negative (TNBC) and non- triple-negati...

background: triple-negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare them with other studies. subjects a...

introduction: triple negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare it with other studies. method: be...