Aim: To assess the role of Triglyceride to High Density lipoprotein cholesterol (TG/HDL_C) ratio as a risk factor of coronary heart disease in women Study design: Cross sectional study. Place and duration of study: The study was conducted in Ayub teaching Hospital, Abbottabad, for 8months from January to August, 2010. Methods: The study was conducted in 100 females known cardiac patients and 50...

Relying on methods other than the determination of turnover rate of triglyceride from the curve of plasma triglyceride radioactivity after administration of labeled precursor, we have confirmed that the endogenous hypertriglyceridemia induced by estrogenization of the chick is accompanied by increased production of triglyceride. Chicks estrogenized with diethylstilbestrol became grossly hypertr...

Obesity is a condition of excess body fat mass with cardiometabolic complications. The levels serum 25-hydroxyvitamin D (25(OH)D) decrease in obesity because it stored adipose tissue compartments and related to dyslipidemia conditions. A high triglyceride/HDL-cholesterol (TG/HDL-C) ratio dyslipidemia. Visceral Adiposity Index (VAI) one the parameters indicating central visceral distribution Thi...

Regucalcin plays a multifunctional role as a regulatory protein in intracellular signaling pathway in many cell types. Regucalcin transgenic (TG) rats have been shown to experience hyperlipidemia with increasing age. This study was undertaken to determine whether lipid components in the adipose and liver tissues are changed in regucalcin TG rats in vivo. Female regucalcin TG rats were used at 7...

The hamster was developed as a model to study very low density lipoprotein (VLDL) metabolism, since, as is the case in humans, the hamster liver was found to synthesize apoB-100 and not apoB-48. The effect of inhibiting fatty acid synthesis on the hepatic secretion of VLDL triglyceride (TG) and apolipoprotein (apo) B-100 in this model was then investigated. In an in vivo study, hamsters were fe...

In 1996 a meta-analysis was published showing that an increase in plasma triglyceride (TG) levels was associated with an increase in CHD risk, even after adjustment for high density lipoprotein cholesterol (HDL-C) levels. Very recently, two studies were published that further extent the early observation and showed the importance of nonfasting plasma triglyceride (TG) levels in the prediction o...

Background: Hypertension is one of the most common diseases with increasing morbidity and mortality. HTN associated cardiovascular risk factors such as insulin resistance (IR) hyperlipidemia. Recently, triglyceride-glucose (TyG) index has been proposed a marker for resistance. Aims Objectives: This study aimed to assess TyG index, triglyceride high-density lipoprotein ratio, other lipid ratios ...

Glucocorticoids are extremely effective anti-inflammatory therapies, but their clinical use is limited due to severe side effects, including osteoporosis, muscle wasting, fat redistribution, and skin thinning. Here we use heavy water labeling and mass spectrometry to measure fluxes through metabolic pathways impacted by glucocorticoids. We combine these methods with measurements of body composi...

A 35-year-old male with alcoholic hypertriglyceridemia due to decreased lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL) activities is reported. The patient had been drinking about 180 ml of whiskey (equivalent to 80 g of 100% ethanol) every day for the last 17 years, and the highest levels of serum triglyceride (TG) and cholesterol were 5,120 mg/dl and 506 mg/dl, respectively. S...

A method is described for preparation of a dissolved oxygen meter (make Aqualytic, Germany) based triglyceride biosensor employing a polyvinyl chloride (PVC) membrane bound lipase, glycerol kinase (GK) and glycerol-3-phosphate oxidase The biosensor measures dissolved O2 utilized in the oxidation of triglyceride (TG) by membrane bound lipase, glycerol kinase (GK) and glycerol-3-phosphate oxidase...