Citation: Doubé W, Carding P, Flanagan K, Kaufman J and Armitage H (2018) Comparing Feedback Types in Multimedia Learning of Speech by Young Children With Common Speech Sound Disorders: Research Protocol for a Pretest Posttest Independent Measures Control Trial. Front. Psychol. 9:444. doi: 10.3389/fpsyg.2018.00444 Comparing Feedback Types in Multimedia Learning of Speech by Young Children With ...

BACKGROUND Analysis of variance (ANOVA), change-score analysis (CSA) and analysis of covariance (ANCOVA) respond differently to baseline imbalance in randomized controlled trials. However, no empirical studies appear to have quantified the differential bias and precision of estimates derived from these methods of analysis, and their relative statistical power, in relation to combinations of lev...

BACKGROUND Use of pretest probability can reduce unnecessary testing. We hypothesize that quantitative pretest probability, linked to evidence-based management strategies, can reduce unnecessary radiation exposure and cost in low-risk patients with symptoms suggestive of acute coronary syndrome and pulmonary embolism. METHODS AND RESULTS This was a prospective, 4-center, randomized controlled...

pretest probability of moderate to severe obstructive sleep apnea.6 A randomized control study is a well-designed clinical trial to examine clinical problems.7 However, our study was a prospective but not a randomized trial and was performed in a single center with a small number of patients. We agree that a study with a better design and larger sample size may solve the issues raised. Finally,...

Hematoma expansion occurs in up to 40% of intracerebral hemorrhage (ICH) patients within 6 hours from the onset. Stopping the expansion is one aim of randomized clinical studies, and an important clinical imperative. CT angiography (CTA) spot sign is a known marker, found in about 30% of patients. Ultraearly hematoma growth (uHG) (expressed as the ratio between hematoma volume [mL] and time [h]...

OBJECTIVES/HYPOTHESIS OtoTrain is a Web-based otoscopy simulator that has previously been shown to have face and content validity. The objective of this study was to evaluate the effectiveness of this Web-based otoscopy simulator in teaching diagnostic otoscopy to novice learners STUDY DESIGN: Prospective, blinded randomized control trial. METHODS Second-year medical students were invited to ...

OBJECTIVES To investigate whether intergroup contact in addition to education is more effective than education alone in reducing stigma of mental illness in adolescents. DESIGN A pragmatic cluster randomised controlled trial compared education alone with education plus contact. Blocking was used to randomly stratify classes within schools to condition. Random allocation was concealed, generat...

OBJECTIVE Data show that many research subjects have difficulty understanding study information using traditional paper consent documents. This study, therefore, was designed to evaluate the effect of an interactive multimedia program on improving parents' and children's understanding of clinical trial concepts and participation. METHODS Parents (n=148) and children (n=135) were each randomis...