1. Cozen W, Bernstein L, Wang F, Press MF, Mack TM. The risk of angiosarcoma following primary breast cancer. Br J Cancer. 1999;81:532--6. 2. Stewart FW, Treves N. Lymphangiosarcoma in postmastectomy lymphedema: a report of six cases in elephantiasis chirurgica. Cancer. 1948;1:64--81. 3. Tomita K, Yokogawa A, Oda Y, Terahata S. Lymphangiosarcoma in postmastectomy lymphedema (Stewart-Treves synd...

Treves syndrome is a rare and aggressive malignancy of the lymphatic vessels. It was first described as arising in chronically lymphoedematous extremities by Stewart and Treves (1948), who noted the condition in six females who had undergone radical mastectomy for breast carcinoma. Since this time, over 300 cases of lymphangiosarcoma arising from the site of chronic lymphoedema have been report...

INTRODUCTION Cutaneous angiosarcoma is a rare and aggressive malignant tumor derived from endothelial cells, which can develop de novo, in irradiated skin, or in areas of chronic lymphedema. Stewart-Treves syndrome describes the association of cutaneous angiosarcoma arising in the setting of lymphedema. This syndrome was first reported in 1948 by Drs Fred Stewart and Norman Treves, who noted 6 ...

S ir Frederick Treves (1853-1923) is best known as the doctor and protector of the Elephant Man, Joseph Merrick (1862-1890) (Figure 1). Broadway plays, a movie, and several books have described Treves’ relationship with this horribly deformed man who is now considered to have had Proteus syndrome rather than the earlier hypothetical diagnosis of neurofibromatosis. Proteus syndrome is a rare dis...

The CA3 and CA1 fields of the mammalian hippocampus are strikingly different in their network architecture: massively recurrent the former, essentially feed-forward the latter. The functional significance of this structural differentiation is not clear, in that neural activity in the two fields shows qualitatively similar features, and computational models generally succeed in mimicking hippoca...

Stewart-Treves syndrome is a rare cutaneous angiosarcoma with a poor prognosis. Physicians must be aware of this lethal syndrome, especially in patients who have been treated for breast cancer with radiation and lymph-node dissection (such as the case reported here). Patients who develop unexplained enlarging plaques of coalescing purple papules should have immediate biopsy for early diagnosis ...

The Elephant Man: A Study in Human Dignity, by ASHLEY MONTAGU, London, Allison & Busby, 1972, pp. x, 140, illus., £2.10. This book gives a vivid account of the life of John Merrick, better known as 'the Elephant Man'. It was Sir Frederick Treves, the well-known London Hospital Surgeon, who discovered Merrick in a 'peep-show' in Whitechapel. Treves befriended him and he was eventually able to li...

According to a theorem of Treves [11], the conserved functionals of the AKNS equation vanish on all pairs of formal Laurent series (q̃, r̃) of a specified form, both of them with a pole of the first order. We propose a new and very simple proof for this statement, based on the theory of Bäcklund transformations; using the same method, we prove that the AKNS conserved functionals vanish on other p...