background: proposing a strategy for sellar reconstruction in endoscopic transsphenoidal transsellar approach for pituitary adenoma. methods: 240 patients with pituitary adenoma underwent pure endoscopic endonasal transsphenoidal surgery. intra-operative csf leaks were classified as grade 0, no observable leak grade 1, csf dripping through an arachnoid membrane defect of less than 1 mm and grad...

objective: prolactinomas are the most common pituitary tumors in pregnant women. we conducted this study on pregnant women with prolactinoma to determine their clinical symptoms and signs and eventual necessity to medical therapy. materials and methods: a descriptive study was performed on 85 pregnant women with prolactinoma.patients were followed up by physical examination, imaging, and perime...

BACKGROUND No data on results of repeated transsphenoidal surgery via the endoscopic technique for patients with persistent or recurrent Cushing's disease are available. DESIGN AND PATIENTS We retrospectively evaluated the remission rates and complications of repeated transsphenoidal surgery via the endoscopic technique in 14 patients with persistent (N = 6) or recurrent (N = 8) Cushing's dis...

Transsphenoidal surgery is the mainstream in the management of sellar and anterior fossa diseases. However, textiloma, as known as cotton left behind during an operation, is rarely reported as a complication of transsphenoidal surgery. In this paper, we present a case of textiloma after transsphenoidal surgery. The patient had been suffering progressive blurred vision and she received transsphe...

Title: Effectiveness of endoscopic endonasal transsphenoidal surgery using a neuronavigation: Clinical results of 178 pituitary adenomas Background: The present study assesses endoscopic endonasal transsphenoidal surgery using neuronavigation for pituitary adenoma. Methods and findings: Data were analyzed from 178 consecutive patients with pituitary adenomas who underwent endoscopic endonasal t...

Background Transsphenoidal secondary operations are a minority but not rare occurrence. How to viably prevent cerebral fluid (CSF)-related complications and confine surgery-caused injury in surgery as minimally possible is huge challenge. This article shares our solution of recycling prior Hadad-Bassagasteguy flap (HBF) along with using small piece free autologous mucosa reconstruct the skull b...

Spontaneous reossification of the sellar floor after transsphenoidal surgery has been rarely reported. Strontium ranelate, a divalent strontium salt, has been shown to increase bone formation, increasing osteoblast activity. We describe an unusual case of a young patient with Cushing's disease who was treated with strontium ranelate for low bone mass who experienced spontaneous sellar reossific...