Trachyonychia is a disorder of the nail unit that most commonly presents with rough, longitudinally ridged nails (opaque trachyonychia) or less frequently, uniform, opalescent nails with pits (shiny trachyonychia). The term trachyonychia refers to 'rough nails.' This article comprehensively reviews the clinical, histologic, and therapeutic aspects of trachyonychia. The authors' preferred evalua...

Trachyonychia or rough nails, may present as an idiopathic disorder of the nails or it can be associated with other dermatological conditions. The dystrophic nail findings seen in trachyonychia are characterized by brittle, thin nails, with excessive longitudinal ridging. The most common histopathologic features associated with trachyonychia are spongiosis and exocytosis of inflammatory cells i...

BACKGROUND Despite efforts to treat trachyonychia, there is no promising treatment modality. OBJECTIVE This study evaluated the efficacy and safety of calcipotriol plus betamethasone dipropionate ointment on trachyonychia. METHODS A total of 39 patients with 432 nails affected by trachyonychia were enrolled. All patients applied calcipotriol/betamethasone ointment once daily without occlusi...

To the Editor, Trachyonychia, also known as 20-nail dystrophy or rough nails, is characterized by surface roughness and opacity of the nail due to extensive longitudinal ridging [1–3] . The condition may be idiopathic or associated with eczema, lichen planus, psoriasis, or alopecia areata [1–3] . Although spontaneous resolution can be expected in trachyonychia, aggressive treatments are necessa...

BACKGROUND/AIMS The term trachyonychia, also known as twenty-nail dystrophy, is used to describe thin, brittle nails with excessive longitudinal ridging. The term twenty-nail dystrophy has been incorrectly applied to other conditions that can affect all twenty nails. Therefore, we have conducted a comprehensive review of the clinical features of trachyonychia and have included a discussion rega...

Turner syndrome is a genetic disorder characterized by abnormalities of the X chromosome. An association with many autoimmune diseases is described as well as skin diseases such as psoriasis, vitiligo and alopecia areata. Trachyonychia is characterized by irregular opaque appearance on the nail plate of all 20 nails. It may be idiopathic or it can be associated with other dermatological disease...

Hong Kong Med J ⎥ Volume 20 Number 5 ⎥ October 2014 ⎥ www.hkmj.org An 86-year-old man presented with leukocytosis in December 2009. Bone marrow biopsy showed chronic myeloid leukaemia in chronic phase and cytogenetic studies showed t(9;22)(q34;q11.2) translocation. He was initially put on imatinib 300 mg daily; subsequently, this was increased to 400 mg daily. He developed pruritic skin rash wi...