bacterial protein toxins have been exploited as therapeutic agents and as vaccines. an issue of deserving interest is development of new generations of vaccines and immune adjuvants. in this study an active assembled recombinant shiga toxin of escherichia coli (rstx1) and its derivatives, recombinant a and b subunits (stx1-a and stx1-b), were used to immunize mice. the elicited antibody respons...

shiga toxin (stx) is the principal virulence factor of shigatoxigenic escherichia coli (stec), a food-born pathogen associated disease with uncomplicated diarrhea or the hemolytic-uremic syndrome. in this study, rabbit polyclonal anti recombinant a, b subunits of shiga toxin and holotoxin antisera were raised and employed for immunological purpose. by immunoblotting, these antisera recognized r...

it is known that the major etiologic agent of pseudomembranous colitis in man is clostridium difficile. with respect to traditional use of almond paste in the treatment of infantile diarrhea, we studied the effects of the aqueous extract of amygdalus communis (aeac) on the growth and toxin production of clostridium difficile in culture medium and the rabbit ligated ileal loop. three groups of m...

Background: T-2 mycotoxin belongs to the Trichothecene family and has damaging effects on the immune system. Objective: To investigate the toxic effect of T-2 toxin on the percentage of peripheral blood B lymphocytes and the potential protective role of selenium and vitamin E. Method: Frequencies of B lymphocytes (CD19+ ) were analyzed after injection of sublethal doses of T-2 toxin into Balb/c...

background: t-2 mycotoxin belongs to the trichothecene family and has damaging effects on the immune system. objective: to investigate the toxic effect of t-2 toxin on the percentage of peripheral blood b lymphocytes and the potential protective role of selenium and vitamin e. method: frequencies of b lymphocytes (cd19+ ) were analyzed after injection of sublethal doses of t-2 toxin into balb/c...