background: oral squamous cell carcinoma (oscc) is one of the most common malignant tumors. its incidence is rated as one among the highest in the world and the use of tobacco in various forms is increasingly associated with the cause of oscc. in oral cancer the study of tumor markers have been limited and several tumor makers with clinical promise needs further evaluation. methods: present stu...

background: detection of cancer at an early stage is of utmost importance to decrease the morbidity and mortality of the disease. apart from the conventional biopsy, non‑invasive methods like analysis of serum and saliva may provide cost‑effective approach for screening a large population. tumor markers are a major part of secondary prevention and thus, the detection of malignancies. the aim of...

Introduction: Sialic acid plays pivotal roles in various critical physiological events at molecular and cellular levels and also pathological processes. Changes in sialic acid concentration are observed in many pathological processes; for example, there are some available data on the evaluated level of sialic acid and neurodegenerative prevalence. It can be proposed that sialic acid can play a ...

conclusions salivary free and total sialic acid, and total protein were higher in the paan consumers compared to non-consumers. due to the carcinogenic effect of smokeless tobacco, measurement of these parameters in saliva may be useful in early detection of oral cancer. results the concentration of salivary free sialic acid (23.21 ± 18.98 mg/l) was significantly increased in paan consumers. th...

1. Serum sialic acid is a reputed cardiovascular risk factor, but the reason why this is so is not clear. We therefore studied its relationship with other known cardiovascular risk factors (particularly those associated with insulin resistance) in 100 healthy young subjects (54 females and 46 males, age 20.7+/-0.89 years). 2. There was a significant univariate correlation between serum total si...

Sialic acid, an acylated derivative of nine carbon sugar neuraminic acid. Serum total sialic acid is a cardiovascular risk factor and associated with increased cardiovascular mortality. The present study was planned to explore the role of serum total sialic acid levels and its correlation with atherogenic index in acute myocardial infarction. It was a case controlled study conducted in the Depa...

Serum sialic acid and total hexosamine values were remarkably elevated in the patients with malignant bone tumor and/or metastasis, in general, but in the great number of the patients with benign bone tumor both these levels remained within the normal range. Whereas, there were some cases with malignant bone tumor showing normal values in both serum sialic acid and total hexosamine levels, but ...

A low sialic acid content in low density lipoprotein (LDL) has been associated with atherogenicity and coronary artery disease (CAD) in many but not all studies. We investigated associations of the sialic acid-to-apolipoprotein B (apoB) ratio of LDL with lipoprotein lipid concentrations, kinetics of LDL, metabolism of cholesterol, and the presence of CAD in 98 subjects (CAD(+), n = 56; CAD(-), ...