background and purpose: vitamin c is administered orally or intravenously for the treatment of burn wounds. however, effects of the topical application of vitamin c remain unclear. this study aimed to evaluate the effects of topical vitamin c solution on the necrotic tissue volume of second-degree burn wounds. methods: this clinical trial was conducted on 30 patients with second-degree burns ad...

Background and Purpose: Vitamin C is administered orally or intravenously for the treatment of burn wounds. However, effects of the topical application of vitamin C remain unclear. This study aimed to evaluate the effects of topical vitamin C solution on the necrotic tissue volume of second-degree burn wounds. Methods: This clinical trial was conducted on 30 patients with second-degree burns a...

BACKGROUND Imagistic methods stand as modern, non-invasive, and objective means of assessing the impact of topical cutaneous therapies. OBJECTIVE This study focuses on the evaluation, by high-frequency ultrasound, of the cutaneous changes induced by topical use of a vitamin C complex at facial level. METHODS A vitamin C-based solution/Placebo moisturizer cream was applied at facial level of...

Fructose, an everyday component of western diet associated to chronic hyperglycemia and enhanced free radical production, impairs endothelial function and supplementation with antioxidants might improve it. In this study we investigated if vitamin E could reverse the microvascular damage elicited by fructose. Male Syrian golden hamsters drank either 10% fructose solution (F) or filtered water (...

BACKGROUND Ocular alkali burns can be associated with a poor visual outcome. The release of collagenases and proteases after the injury leads to corneoscleral melting. The role of topical steroids in such patients is controversial as they have been postulated to exacerbate corneoscleral melting. METHODS 30 patients were reviewed retrospectively after admission to King's College Hospital with ...

BACKGROUND Virtually all plants and animals protect themselves from the sun using vitamins C and E. OBJECTIVE The purpose of this study was to see if a combination of topical vitamins C and E is better for UV protection to skin than an equivalent concentration of topical vitamin C or E alone. METHODS We developed a stable aqueous solution of 15% L-ascorbic acid (vitamin C) and 1% alpha-toco...

Because of the ever-increasing incidence of ultraviolet light B (UVB)-induced skin cancer, considerable attention is being paid to prevention through the use of both sunscreens and after sun treatments, many of which contain antioxidants. Vitamin E is included as an antioxidant in many sunscreens and lotions currently on the market. Studies examining the efficacy of vitamin E as a topical preve...

BACKGROUND The influence of ageing on the density of the functional entities of the papillae containing nutritive capillaries, here in terms as the papillary index, and the effect of topically applied vitamin C were investigated by confocal laser scanning microscopy (CLSM) in vivo. METHODS The age dependency of the papillary index was determined by CLSM on 3 different age groups. Additionally...