objectives: nitric oxide (no) is a signaling molecule that mediates mechanical bone loading. cyclic guanosine 3', 5' monophosphate (cgmp) is a no-induced effector molecule. the aim of this study was to assess the effect of no-cgmp pathway on orthodontic tooth movement (otm) in rats by use of two phosphodiesterase 5 (pde5) inhibitors namely sildenafil and tadalafil as chemical tools. materials a...

Duration of treatment is one of the main concerns of patients undergoing orthodontic treatment. Fixed orthodontic treatment lasts up to 2 to 3 years increasing the risk of external root resorption, periodontal problems and patient compliance [1]. Clinicians are constantly striving towards developing strategies to enhance the rate of orthodontic tooth movement. An increase in in-depth knowledge ...

introduction: corticotomy-facilitated orthodontics provides a means for rapidly moving teeth purportedly with little damaging effects to the periodontium and with greatly reduced treatment time. the aim of this study was to enhance the orthodontic tooth movement by reducing the cortical bone layer (resistant to bone re-sorption relative to spongious bone) following erbium, chromium doped yttriu...

objectives: fluoxetine is a selective serotonin re-uptake inhibitor (ssri) widely used for depression, bipolar disorder, anxiety and obsessive-compulsive disorder. the aim of this study was to assess the effect of fluoxetine on orthodontic tooth movement (otm) in rats. materials and methods: forty-five male wistar rats were randomly divided into three groups namely the control group (no medicat...

The case of the Boy with the Golden Tooth, a "miracle" in a remote village in Silesia, in what is today southwestern Poland, was reported extensively in 1593. Here we report that the hoax, perpetrated by someone close to the family and with knowledge of goldsmith techniques, is the first documented case of the use of a molded gold crown. Using period instruments available to goldsmiths and a 0....