نتایج جستجو برای: tnbc

تعداد نتایج: 1923  

Journal: :galen medical journal 0
mehrnoosh etemadi students’ scientific research center, tehran university of medical sciences, tehran mohammad mahdi zamani students’ scientific research center, tehran university of medical sciences, tehran department of anesthesiology and critical care, tehran university of medical sciences, tehran amir masoud nazemi blood transfusion research center, high institute for research and education in transfusion medicine, iranian blood transfusion organization, tehran afsaneh rajabiani department of pathology, school of medicine, tehran university of medical sciences, tehran alireza abdollahi department of pathology, school of medicine, tehran university of medical sciences, tehran

background : breast cancer is one of the most frequent malignancies among iranian women. triple-negative breast cancer (tnbc) is referred to a type of breast cancer which three biomarkers of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (her2), are negative. materials and methods: in this case control study, immunohistopathologic data of patients with tn...

Introduction: Triple-negative breast cancer (TNBC) is a type of breast cancer that is negative for estrogen receptor, progesterone receptor, and HER2. This study aimed to evaluate the clinical outcomes and short-term prognosis of this type of cancer compared with other subtypes of breast cancer. Methods: A cross-sectional study was conducted on 108 women with invasive breast cancer. The patie...

Journal: :acta medica iranica 0
mahdi aghili department of radiation oncology, cancer institute, school of medicine, tehran university of medical sciences, tehran, iran. marzieh lashkari department of radiation oncology, cancer institute, school of medicine, tehran university of medical sciences, tehran, iran. amir hosein farrokhpey department of general medicine, tehran university of medical sciences, tehran, iran. shahrzad izadi department of surgery, zanjan university of medical sciences, zanjan, iran.

this study focused on triple-negative breast cancer (tnbc) that is characterized by the lack of expression of estrogen receptor (er), progesterone receptor (pr), and human epidermal growth factor receptor 2 (her-2). the primary goal of this study was to describe the relation between triple-negative receptor status and survival. this is the first study about triple-negative breast cancer in our ...

Journal: :international journal of hematology-oncology and stem cell research 0
alireza abdollahi associate professor of pathology, department of pathology, imam hospital complex, tehran university of medical sciences, tehran, iran mehrnoosh etemadi students of scientific research centre, tehran university of medical sciences, tehran, iran

background : triple-negative breast cancers (tnbc) are defined as breast cancers with lack of estrogen and progesterone receptors and no overexpression of human epidermal growth factor receptor 2 (her2). this study was performed to determine the frequency and pathologic features of tnbc in iranian patients. subjects and methods: this cross-sectional study was performed on patients with breast c...

Abbas Ahmadi, Anvar Elyasi, Karim Rahimi, Mohammad Abdi, Mohammad-Nazir Menbari, Nikoo Darvishi, Samira Mohammadi-Yeganeh, Vahedeh Hosseini,

Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...

Journal: :international journal of hematology-oncology and stem cell research 0
mehrzad mirzania department of medical oncology, cancer research center, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, iran seyed reza safaee department of medical oncology, cancer research center, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, iran farhad shahi department of medical oncology, cancer research center, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, iran issa jahanzad department of pathology, cancer institute, imam khomeini hospital complex, tehran university of medical sciences, tehran, iran ghazal zahedi department of internal medicine, imam khomeini hospital, tehran university of medical sciences, tehran, iran reza mehdizadeh breast cancer research center, academic center for education culture and research (acecr), tehran, iran

background: triple-negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare them with other studies. subjects a...

Journal: :international journal of hematology-oncology and stem cell research 0
mehrzad mirzania mehrzad mirzania md, hematology and medical oncology department, cancer research center , cancer institute, imam khomeini hospital complex, tehran university of medical sciences(tums). seyed reza safaee farhad shahi issa jahanzad ghazal zahedi reza mehdizadeh

introduction: triple negative breast cancers (tnbc) have a more aggressive course and are associated with poorer prognosis in comparison with other subtypes of breast cancer. one of the most common subtypes of tnbc is basal-like. the aim of this study was to investigate clinicopathological characteristics and clinical course of tnbc in iranian women and compare it with other studies. method: be...

Journal: :Clinical advances in hematology & oncology : H&O 2014
Khurram Tariq Arezo Farhangi Fauzia Rana

PURPOSE This study was designed to compare mean age, ethnicity, smoking history, family history of breast cancer, and stage at diagnosis in patients with triple-negative breast cancer (TNBC) vs non-TNBC at an inner city university program. METHODS We reviewed data in our tumor registry on patients seen between January 2000 and December 2005, and identified a total of 445 patients with various...

2016
Sanghwa Kim Hyung Seok Park Jee Ye Kim Jegyu Ryu Seho Park Seung Il Kim

PURPOSE The optimum local surgical strategy regarding breast-conserving therapy (BCT) for triple-negative breast cancer (TNBC) is controversial. To investigate whether BCT is appropriate for patients with TNBC, we evaluated the clinical outcomes of BCT in women with TNBC compared to those of women without TNBC, using a large, single-center cohort. MATERIALS AND METHODS We performed a retrospe...

2018
Zhixian Liu Mengyuan Li Zehang Jiang Xiaosheng Wang

Triple-negative breast cancer (TNBC) is a high-risk malignancy due to its high capacity for invasion and lack of targeted therapy. Immunotherapy continues to demonstrate efficacy in a variety of cancers, and thus may be a promising strategy for TNBC given the limited therapeutic options currently available for TNBC. In this study, we performed an exhaustive analysis of immunogenic signatures in...

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