Two methods for determining ranitidine hydrochloride (RNH) in pure drug and in formulations using potassium iodate and dichlorofuorescein are described. Titrimetry involves the oxidation of RNH by a known excess of potassium iodate in acidic conditions followed by iodometric determination of surplus iodate. In spectrophotometry also, the drug is oxidized by a large excess of iodate and the iodi...

A sequential separation scheme has been devised for the quantitative analytical separation of 27 different metal ions. Five different Chromatographic and ion-exchange columns are used to separate the metal ions into groups. The metal ions of each group are eluted separately from each column by means of selective eluents. Following separation, the metal ions are determined by titrimetry, flame s...

One titrimetric and two spectrophotometric procedures have been reported for the determination of albendazole and its tablets. Using titrimetry, the drug was titrated directly with Chloramine-T under acidic conditions using a Methyl Orange indicator. The spectrophotometric procedures involve treating the sample solution with a measured excess of Chloramine-T in an acid medium, followed by an es...

two rapid, simple, sensitive and cost-effective titrimetric and spectr-ophotometric methods are described for the determination of albendazole (alb) in bulk drug and in pharmaceuticals. in titrimetry (method a), alb is oxidized by a known excess of potassium permanganate (kmno 4 ) in h 2 so 4 medium followed by the determination of unreacted permanganate by titration with ferrous ammonium sulph...

superior speed and simplicity with little sacrifice in accuracy and precision. Phenytoin sodium (DPH) forms phenytoin silver collosol quantitatively with silver nitrate solution. The reaction between phenytoin sodium and silver nitrate reveals a 1 : 1 molar ratio as illustrated in Chart 1. However, there was no accurate method available to determine the titration end-point. Therefore, gravimetr...

* Author for Correspondence: E-mail: [email protected], Mobile: +91-944 893 910 5; Fax: 0091-821-2421263, 2516133 † The September 2009 Issue of the Journal had got delayed. To avoid delay in publication, this article has been included in the present Issue even though it was accepted after September 2009. Determination of Drug Content of Pharmaceuticals Containing Lamotrigine by Titrimetry ...

Four new methods using titrimetry and spectrophotometry are described for the rapid determination of amoxycillin in bulk drug and dosage forms. In direct titrimetry (Method A), the drug is titrated with bromate–bromide mixture in acid medium using methyl orange indicator. Back titrimetry (Method B) entails adding a known excess amount of bromatebromide mixture to the drug solution in acid mediu...