aim : the aim of this study was to determine the prevalence of celiac disease in iranian patients suffering from chronic depression or schizophrenia. background : psychiatric disorders are common in untreated celiac disease. patients and methods : two hundred iranian inpatient men with in chronic phase of depressive disorders or schizophrenia, and 200 age-matched healthy male subjects were scre...

celiac disease has been associated with other autoimmune disorders such as autoimmune hepatitis, moreover it is known that t cell mediated immune response to dietary gluten and released cytokines are important for the entheropathy seen in celiac disease. we investigated celiac autoantibodies in patients with autoimmune hepatitis (aih), and chronic hepatitis b (chb). sera from 84 patients with a...

BACKGROUND Tissue transglutaminase is now recognized as the autoantigen for antiendomysial antibodies. Antibodies to tissue transglutaminase have been proposed as a valuable test for coeliac disease. OBJECTIVE To determine the value of antibodies to tissue transglutaminase in the diagnosis of coeliac disease in our outpatient population. METHODS Patients who underwent serological tests for ...

OBJECTIVE a strong association has been observed between celiac disease, generally its silent clinical form, and autoimmune disorders. A potential correlation with inflammatory bowel disease has also been suggested. Anti-tissue transglutaminase antibodies have been detected in Crohn´s disease. We investigated the prevalence of celiac disease in patients with autoimmune diabetes and in Crohn´s d...

OBJECTIVE Serum IgA-class tissue transglutaminase antibody has proved effective in screening for coeliac disease. The response to a gluten-free diet has been assessed on the basis of small-intestinal morphology. We investigated whether the tissue transglutaminase antibody test could substitute biopsy in this respect, and whether the test is better than the endomysial antibody test in follow-up....

BACKGROUND Aetiopathogenesis of psoriasis is complex and not yet well known. In recent years, it has been observed that psoriasis can coexist with clinically asymptomatic celiac disease and a gluten-free diet helps to obtain remission, even in patients with very chronic lesions. OBJECTIVE The aim of our work was to investigate how often the positive titres of antibodies characteristic for cel...

Celiac disease is a chronic illness of the small bowel caused by gliadin intolerance in genetically predisposed subjects. The aim of this study was to investigate serum levels of IgA and IgG antigliadin antibodies, IgA antiendomysial antibodies, and IgA anti-tissue transglutaminase antibodies in 169 patients with autoimmune thyroid diseases, i.e. chronic thyroiditis and Graves' disease. Antiend...

AIMS To compare and contrast the sensitivity, specificity, and positive predictive values of IgA antibodies to guinea pig tissue transglutaminase (ELISA), endomysium, and reticulin (immunofluorescence), and gliadin (ELISA), and IgG antibodies to gliadin and tissue transglutaminase. METHODS Sera from 27 newly diagnosed patients with coeliac disease, 65 biopsied gastrointestinal disease control...

BACKGROUND The conventional coeliac disease antibody tests require patient's sera, and are laborious and time-consuming. AIM To evaluate a newly developed rapid whole blood test in coeliac disease antibody detection, and its suitability for office use. METHODS Endogenous tissue transglutaminase found in red blood cells in a whole blood fingertip or venous sample is liberated upon haemolysis...

BACKGROUND Serologic methods have been used widely to test for celiac disease and have gained importance in diagnostic definition and in new epidemiologic findings. However, there is no standardization, and there are no reference protocols and materials. METHODS The European working group on Serological Screening for Celiac Disease has defined robust noncommercial test protocols for immunoglo...